Difference between revisions of "YkfA"

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|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
 
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU12970 ykfA]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU12970 ykfA]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 25 kDa, 5.409   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 25 kDa, 5.409   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[dppE]]'', ''[[ykfB]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[dppE]]'', ''[[ykfB]]''
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13154&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU12970 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU12970 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU12970 Advanced_DNA]
 
|-
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ykfA_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ykfA_context.gif]]

Revision as of 12:37, 13 May 2013

  • Description: similar to immunity to bacteriotoxins

Gene name ykfA
Synonyms
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: ykfA
MW, pI 25 kDa, 5.409
Gene length, protein length 702 bp, 234 aa
Immediate neighbours dppE, ykfB
Sequences Protein DNA Advanced_DNA
Genetic context
YkfA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YkfA expression.png















Categories containing this gene/protein

toxins, antitoxins and immunity against toxins

This gene is a member of the following regulons

CodY regulon

The gene

Basic information

  • Locus tag: BSU12970

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: peptidase S66 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulatory mechanism: CodY: transcription repression PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Virginie Molle, Yoshiko Nakaura, Robert P Shivers, Hirotake Yamaguchi, Richard Losick, Yasutaro Fujita, Abraham L Sonenshein
Additional targets of the Bacillus subtilis global regulator CodY identified by chromatin immunoprecipitation and genome-wide transcript analysis.
J Bacteriol: 2003, 185(6);1911-22
[PubMed:12618455] [WorldCat.org] [DOI] (P p)