Difference between revisions of "RpsS"

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* '''Regulation:'''  
 
* '''Regulation:'''  
 
** [[RelA]] dependent downregulation (Class I) during stringent response {{PubMed|11948165}}
 
** [[RelA]] dependent downregulation (Class I) during stringent response {{PubMed|11948165}}
 +
** strongly repressed in response to glucose starvation in M9 medium {{PubMed|23033921}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
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=References=
 
=References=
'''Additional publications:''' {{PubMed|23002217}}
+
'''Additional publications:''' {{PubMed|23033921,23002217}}
 
<pubmed> 19653700 9371452 11948165 8635744</pubmed>
 
<pubmed> 19653700 9371452 11948165 8635744</pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 19:41, 8 October 2012

Gene name rpsS
Synonyms
Essential yes PubMed
Product ribosomal protein S19 (BS19)
Function translation
Gene expression levels in SubtiExpress: rpsS
Interactions involving this protein in SubtInteract: RpsS
MW, pI 10 kDa, 10.585
Gene length, protein length 276 bp, 92 aa
Immediate neighbours rplB, rplV
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RpsS context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RpsS expression.png















Categories containing this gene/protein

translation, essential genes, universally conserved proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU01200

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
    • SigA two promoters, about 140bp and 200bp upstream of the start codon PubMed
  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
    • strongly repressed in response to glucose starvation in M9 medium PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Matthew A Lauber, William E Running, James P Reilly
B. subtilis ribosomal proteins: structural homology and post-translational modifications.
J Proteome Res: 2009, 8(9);4193-206
[PubMed:19653700] [WorldCat.org] [DOI] (P p)

Christine Eymann, Georg Homuth, Christian Scharf, Michael Hecker
Bacillus subtilis functional genomics: global characterization of the stringent response by proteome and transcriptome analysis.
J Bacteriol: 2002, 184(9);2500-20
[PubMed:11948165] [WorldCat.org] [DOI] (P p)

X Li, L Lindahl, Y Sha, J M Zengel
Analysis of the Bacillus subtilis S10 ribosomal protein gene cluster identifies two promoters that may be responsible for transcription of the entire 15-kilobase S10-spc-alpha cluster.
J Bacteriol: 1997, 179(22);7046-54
[PubMed:9371452] [WorldCat.org] [DOI] (P p)

J W Suh, S A Boylan, S H Oh, C W Price
Genetic and transcriptional organization of the Bacillus subtilis spc-alpha region.
Gene: 1996, 169(1);17-23
[PubMed:8635744] [WorldCat.org] [DOI] (P p)