Difference between revisions of "HypO"
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|style="background:#ABCDEF;" align="center"|'''Function''' || protection against NaOCl stress | |style="background:#ABCDEF;" align="center"|'''Function''' || protection against NaOCl stress | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU07830 hypO] |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 25 kDa, 5.667 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 25 kDa, 5.667 | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[treR]]'', ''[[yfkN]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[treR]]'', ''[[yfkN]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU07830 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU07830 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU07830 Advanced_DNA] |
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|colspan="2" | '''Genetic context''' <br/> [[Image:yfkO_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yfkO_context.gif]] | ||
Revision as of 12:21, 13 May 2013
- Description: NAD(P)H-flavin nitroreductase
| Gene name | hypO |
| Synonyms | yfkO |
| Essential | no |
| Product | NAD(P)H-flavin nitroreductase |
| Function | protection against NaOCl stress |
| Gene expression levels in SubtiExpress: hypO | |
| MW, pI | 25 kDa, 5.667 |
| Gene length, protein length | 663 bp, 221 aa |
| Immediate neighbours | treR, yfkN |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
electron transport/ other, resistance against oxidative and electrophile stress
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU07830
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: nitroreductase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O34475
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: hypO PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Haike Antelmann, University of Greifswald, Germany
Your additional remarks
References
Original articles
Palm GJ, Khanh Chi B, Waack P, Gronau K, Becher D, Albrecht D, Hinrichs W, Read RJ, Antelmann H. Structural insights into the redox-switch mechanism of the MarR/DUF24-type regulator HypR. Nucleic Acids Res. 2012, Jan 11. [Epub ahead of print] PubMed
