Difference between revisions of "DegA"

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|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
 
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU10840 degA]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU10840 degA]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 36 kDa, 5.784   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 36 kDa, 5.784   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yisR]]'', ''[[iolX]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yisR]]'', ''[[iolX]]''
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12923&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU10840 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU10840 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU10840 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:degA_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:degA_context.gif]]

Revision as of 12:30, 13 May 2013

  • Description: transcriptional activator involved in the degradation of glutamine phosphoribosylpyrophosphate amidotransferase

Gene name degA
Synonyms
Essential no
Product transcriptional activator (LacI family)
Function unknown
Gene expression levels in SubtiExpress: degA
MW, pI 36 kDa, 5.784
Gene length, protein length 1011 bp, 337 aa
Immediate neighbours yisR, iolX
Sequences Protein DNA Advanced_DNA
Genetic context
DegA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
DegA expression.png
























Categories containing this gene/protein

transcription factors and their control

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU10840

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information: the mRNA is very stable (half-life > 15 min) PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

G Hambraeus, C von Wachenfeldt, L Hederstedt
Genome-wide survey of mRNA half-lives in Bacillus subtilis identifies extremely stable mRNAs.
Mol Genet Genomics: 2003, 269(5);706-14
[PubMed:12884008] [WorldCat.org] [DOI] (P p)

L B Bussey, R L Switzer
The degA gene product accelerates degradation of Bacillus subtilis phosphoribosylpyrophosphate amidotransferase in Escherichia coli.
J Bacteriol: 1993, 175(19);6348-53
[PubMed:8407808] [WorldCat.org] [DOI] (P p)