Difference between revisions of "MrnC"

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|style="background:#ABCDEF;" align="center"|'''Function''' || maturation of 23S rRNA
 
|style="background:#ABCDEF;" align="center"|'''Function''' || maturation of 23S rRNA
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU00950 mrnC]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU00950 mrnC]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/tRNA_charging.html tRNA charging]'''
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/tRNA_charging.html tRNA charging]'''
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[cysS]]'', ''[[yacO]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[cysS]]'', ''[[yacO]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB11871&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU00950 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU00950 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU00950 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:yazC_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yazC_context.gif]]

Revision as of 11:57, 13 May 2013

  • Description: RNase Mini-III

Gene name mrnC
Synonyms yazC
Essential no
Product RNase Mini-III
Function maturation of 23S rRNA
Gene expression levels in SubtiExpress: mrnC
Metabolic function and regulation of this protein in SubtiPathways:
tRNA charging
MW, pI 16 kDa, 9.153
Gene length, protein length 429 bp, 143 aa
Immediate neighbours cysS, yacO
Sequences Protein DNA Advanced_DNA
Genetic context
YazC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MrnC expression.png




























Categories containing this gene/protein

Rnases, translation

This gene is a member of the following regulons

T-box

The gene

Basic information

  • Locus tag: BSU00950

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: RNase III family (but lacks the dsRNA-binding domain)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: RplC binding to the precursor 23S rRNA stimulates MrnC activity PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism: T-box, overlaps a transcription terminator upstream of cysE: transcription antitermination PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Ciaran Condon, IBPC, Paris, France Homepage

David Bechhofer, Mount Sinai School, New York, USA Homepage

Your additional remarks

References