Difference between revisions of "MurF"
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|style="background:#ABCDEF;" align="center"|'''Function''' || peptidoglycan precursor biosynthesis | |style="background:#ABCDEF;" align="center"|'''Function''' || peptidoglycan precursor biosynthesis | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU04570 murF] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/cellwall.html Cell wall]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/cellwall.html Cell wall]''' | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ddl]]'', ''[[cshA]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ddl]]'', ''[[cshA]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU04570 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU04570 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU04570 Advanced_DNA] |
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|colspan="2" | '''Genetic context''' <br/> [[Image:murF_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:murF_context.gif]] | ||
Revision as of 12:11, 13 May 2013
- Description: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine synthetase
| Gene name | murF |
| Synonyms | ydbQ |
| Essential | yes PubMed |
| Product | UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso- 2,6- diaminopimeloyl-D-alanyl-D-alanine synthetase |
| Function | peptidoglycan precursor biosynthesis |
| Gene expression levels in SubtiExpress: murF | |
| Metabolic function and regulation of this protein in SubtiPathways: Cell wall | |
| MW, pI | 49 kDa, 5.337 |
| Gene length, protein length | 1371 bp, 457 aa |
| Immediate neighbours | ddl, cshA |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
cell wall synthesis, biosynthesis of cell wall components, cell envelope stress proteins (controlled by SigM, V, W, X, Y), essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU04570
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine + D-alanyl-D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine (according to Swiss-Prot)
- Protein family: murCDEF family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- UniProt: P96613
- KEGG entry: [2]
- E.C. number: 6.3.2.10
Additional information
Expression and regulation
- Operon:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
