Difference between revisions of "Hmp"

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|style="background:#ABCDEF;" align="center"|'''Function''' || resistance to NO  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || resistance to NO  
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU13040 hmp]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU13040 hmp]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress]'''
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress]'''
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ykhA]]'', ''[[ykzH]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ykhA]]'', ''[[ykzH]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13161&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU13040 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU13040 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU13040 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:hmp_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:hmp_context.gif]]

Revision as of 12:37, 13 May 2013

  • Description: flavohemoglobin, involved in resistance to nitric oxide (NO), essential for long-term survival under anaerobic conditions

Gene name hmp
Synonyms ykiA
Essential no
Product flavohemoglobin
Function resistance to NO
Gene expression levels in SubtiExpress: hmp
Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 44 kDa, 5.705
Gene length, protein length 1197 bp, 399 aa
Immediate neighbours ykhA, ykzH
Sequences Protein DNA Advanced_DNA
Genetic context
Hmp context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Hmp expression.png




























Categories containing this gene/protein

electron transport/ other, resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)

This gene is a member of the following regulons

NsrR regulon, ResD regulon

The gene

Basic information

  • Locus tag: BSU13040

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 2 NO + 2 O2 + NAD(P)H = 2 NO3- + NAD(P)+ (according to Swiss-Prot)
  • Protein family: FAD-binding FR-type domain (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed under anaerobic conditions (ResD) PubMed
    • induced by nitric oxide under anaerobic conditions (NsrR) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References