ZnuB

• Description: ABC transporter for zinc (permease)
  
  

Gene name	znuB
Synonyms	yceA
Essential	no
Product	ABC transporter for zinc (permease)
Function	zinc uptake
Gene expression levels in SubtiExpress: znuB
Interactions involving this protein in SubtInteract: ZnuB
Metabolic function and regulation of this protein in SubtiPathways: Stress
MW, pI	30 kDa, 10.375
Gene length, protein length	840 bp, 280 aa
Immediate neighbours	znuC, yceB
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, trace metal homeostasis (Cu, Zn, Ni, Mn, Mo), membrane proteins

This gene is a member of the following regulons

Zur regulon

The gene

Basic information

• Locus tag: BSU02870

Phenotypes of a mutant

• • reduced genetic competence, can be rescued by the addition of excess zinc PubMed
  • reduced expression of the comFA-comFB-comFC-yvyF-flgM-yvyG-flgK-flgL operon PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ABC-3 integral membrane protein family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: ZnuA-ZnuB-ZnuC PubMed

• Localization: cell membrane PubMed

Database entries

• Structure:

• UniProt: O34610

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: znuA-znuC-znuB PubMed

• Expression browser: znuB PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by zinc starvation (Zur) PubMed

• Regulatory mechanism:
  • Zur: transcription repression in the presence of zinc PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: