Difference between revisions of "TatCD"

From SubtiWiki
Jump to: navigation, search
Line 41: Line 41:
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
<br/><br/><br/><br/>
+
<br/><br/>
<br/><br/><br/><br/>
 
 
 
 
 
<br/><br/><br/><br/>
 
  
 
= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
Line 117: Line 113:
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=tatCD_286048_286776_1 tatCD] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=tatCD_286048_286776_1 tatCD] {{PubMed|22383849}}
  
* '''Sigma factor:'''  
+
* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
Line 149: Line 145:
  
 
=References=
 
=References=
 
+
== Reviews ==
 +
<pubmed> 22683878 </pubmed>
 +
== Original publications ==
 
<pubmed>11007775,15554971,22544248,11007775, 19383693, 19395490 19616508 </pubmed>
 
<pubmed>11007775,15554971,22544248,11007775, 19383693, 19395490 19616508 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 11:51, 26 November 2012

  • Description: component of the TatAdCd twin-arginine translocase

Gene name tatCD
Synonyms ycbT
Essential no
Product component of the twin-arginine translocation pathway
Function TAT protein secretion
Gene expression levels in SubtiExpress: tatCD
Interactions involving this protein in SubtInteract: TatCD
Metabolic function and regulation of this protein in SubtiPathways:
Protein secretion
MW, pI 27 kDa, 9.342
Gene length, protein length 735 bp, 245 aa
Immediate neighbours tatAD, pcp
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
TatCD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
TatCD expression.png















Categories containing this gene/protein

phosphate metabolism, protein secretion, membrane proteins

This gene is a member of the following regulons

PhoP regulon

The gene

Basic information

  • Locus tag: BSU02640

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: translocation of PhoD PubMed
  • Protein family: tatC family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
    • expressed under conditions of phosphate limitation (PhoP) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Oscar Kuipers, University of Groningen, The Netherlands Homepage

Your additional remarks

References

Reviews

Tracy Palmer, Ben C Berks
The twin-arginine translocation (Tat) protein export pathway.
Nat Rev Microbiol: 2012, 10(7);483-96
[PubMed:22683878] [WorldCat.org] [DOI] (I e)

Original publications

Carmine G Monteferrante, Jacopo Baglieri, Colin Robinson, Jan Maarten van Dijl
TatAc, the third TatA subunit of Bacillus subtilis, can form active twin-arginine translocases with the TatCd and TatCy subunits.
Appl Environ Microbiol: 2012, 78(14);4999-5001
[PubMed:22544248] [WorldCat.org] [DOI] (I p)

Olga V Nolandt, Torsten H Walther, Siegmar Roth, Jochen Bürck, Anne S Ulrich
Structure analysis of the membrane protein TatC(d) from the Tat system of B. subtilis by circular dichroism.
Biochim Biophys Acta: 2009, 1788(10);2238-44
[PubMed:19616508] [WorldCat.org] [DOI] (P p)

Anja N J A Ridder, Esther J de Jong, Jan D H Jongbloed, Oscar P Kuipers
Subcellular localization of TatAd of Bacillus subtilis depends on the presence of TatCd or TatCy.
J Bacteriol: 2009, 191(13);4410-8
[PubMed:19395490] [WorldCat.org] [DOI] (I p)

Robyn T Eijlander, Magdalena A Kolbusz, Erwin M Berendsen, Oscar P Kuipers
Effects of altered TatC proteins on protein secretion efficiency via the twin-arginine translocation pathway of Bacillus subtilis.
Microbiology (Reading): 2009, 155(Pt 6);1776-1785
[PubMed:19383693] [WorldCat.org] [DOI] (P p)

Jan D H Jongbloed, Ulrike Grieger, Haike Antelmann, Michael Hecker, Reindert Nijland, Sierd Bron, Jan Maarten van Dijl
Two minimal Tat translocases in Bacillus.
Mol Microbiol: 2004, 54(5);1319-25
[PubMed:15554971] [WorldCat.org] [DOI] (P p)

J D Jongbloed, U Martin, H Antelmann, M Hecker, H Tjalsma, G Venema, S Bron, J M van Dijl, J Müller
TatC is a specificity determinant for protein secretion via the twin-arginine translocation pathway.
J Biol Chem: 2000, 275(52);41350-7
[PubMed:11007775] [WorldCat.org] [DOI] (P p)