Difference between revisions of "FeuB"

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|style="background:#ABCDEF;" align="center"|'''Function''' || [[acquisition of iron]]
 
|style="background:#ABCDEF;" align="center"|'''Function''' || [[acquisition of iron]]
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU01620 feuB]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU01620 feuB]
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/FeuB FeuB]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/FeuB FeuB]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[feuC]]'', ''[[feuA]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[feuC]]'', ''[[feuA]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB11938&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU01620 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU01620 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU01620 Advanced_DNA]
 
|-
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:feuB_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:feuB_context.gif]]

Revision as of 12:00, 13 May 2013

  • Description: ABC transporter for the siderophores Fe-enterobactin and Fe-bacillibactin (integral membrane protein)

Gene name feuB
Synonyms
Essential no
Product ABC transporter for the siderophores Fe-enterobactin
and Fe-bacillibactin (integral membrane protein)
Function acquisition of iron
Gene expression levels in SubtiExpress: feuB
Interactions involving this protein in SubtInteract: FeuB
Metabolic function and regulation of this protein in SubtiPathways:
Stress, Metal ion homeostasis
MW, pI 35 kDa, 9.539
Gene length, protein length 1002 bp, 334 aa
Immediate neighbours feuC, feuA
Sequences Protein DNA Advanced_DNA
Genetic context
FeuB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FeuB expression.png




























Categories containing this gene/protein

ABC transporters, acquisition of iron, iron metabolism, membrane proteins

This gene is a member of the following regulons

Btr regulon, CitB regulon, Fur regulon

The gene

Basic information

  • Locus tag: BSU01620

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: FecCD subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed in the presence of iron (Fur, CitB) PubMed
    • induced in the presence of iron chelators bacillibactin or enterobactin (Btr) PubMed
  • Regulatory mechanism:
    • Fur: transcription repression PubMed
    • CitB: binding to the iron responsive element in the absence of iron
    • Btr: transcription activation in the presence of the co-activators bacillibactin or enterobactin PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References