Difference between revisions of "RadA"

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|colspan="2" | '''Genetic context''' <br/> [[Image:radA_context.gif]]
 
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Revision as of 13:07, 8 August 2012

  • Description: suppressor of recU and recB mutations, participates in the stabilization and or processing of holliday junction intermediates

Gene name radA
Synonyms sms, yacJ
Essential no
Product DNA repair protein homolog
Function homologous recombination
Gene expression levels in SubtiExpress: radA
Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 49 kDa, 8.128
Gene length, protein length 1374 bp, 458 aa
Immediate neighbours clpC, disA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RadA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RadA expression.png




























Categories containing this gene/protein

DNA repair/ recombination, general stress proteins (controlled by SigB), heat shock proteins

This gene is a member of the following regulons

CtsR regulon, SigB regulon

The gene

Basic information

  • Locus tag: BSU00870

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: RadA subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism: CtsR: transcription repression PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References