Difference between revisions of "MnaA"
| Line 14: | Line 14: | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of teichoic acid | |style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of teichoic acid | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU35660 mnaA] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 5.469 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 5.469 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[tagU]]'', ''[[gtaB]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[tagU]]'', ''[[gtaB]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU35660 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU35660 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU35660 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yvyH_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yvyH_context.gif]] | ||
Revision as of 14:00, 13 May 2013
- Description: UDP-N-acetylglucosamine 2-epimerase
| Gene name | mnaA |
| Synonyms | yvyH |
| Essential | yes PubMed |
| Product | UDP-N-acetylglucosamine 2-epimerase |
| Function | biosynthesis of teichoic acid |
| Gene expression levels in SubtiExpress: mnaA | |
| MW, pI | 42 kDa, 5.469 |
| Gene length, protein length | 1140 bp, 380 aa |
| Immediate neighbours | tagU, gtaB |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
cell wall synthesis, biosynthesis of cell wall components, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU35660
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine (according to Swiss-Prot)
- Protein family: UDP-N-acetylglucosamine 2-epimerase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure: 1O6C
- UniProt: P39131
- KEGG entry: [2]
- E.C. number: 5.1.3.14
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Blazenka Soldo, Vladimir Lazarevic, Harold M Pooley, Dimitri Karamata
Characterization of a Bacillus subtilis thermosensitive teichoic acid-deficient mutant: gene mnaA (yvyH) encodes the UDP-N-acetylglucosamine 2-epimerase.
J Bacteriol: 2002, 184(15);4316-20
[PubMed:12107153]
[WorldCat.org]
[DOI]
(P p)
