Difference between revisions of "NagR"
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|style="background:#ABCDEF;" align="center"|'''Function''' || probably regulator of the putative ''[[nagA]]-[[nagB]]-[[yvoA]]'' operon | |style="background:#ABCDEF;" align="center"|'''Function''' || probably regulator of the putative ''[[nagA]]-[[nagB]]-[[yvoA]]'' operon | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU35030 nagR] |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbohydrate_metabolic_pathways.html Sugar catabolism], [http://subtiwiki.uni-goettingen.de/pathways/murein/index.html Murein recycling]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbohydrate_metabolic_pathways.html Sugar catabolism], [http://subtiwiki.uni-goettingen.de/pathways/murein/index.html Murein recycling]''' | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[nagB]]'', ''[[yvnB]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[nagB]]'', ''[[yvnB]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU35030 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU35030 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU35030 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yvoA_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yvoA_context.gif]] | ||
Revision as of 13:57, 13 May 2013
- Description: transcriptional regulator (GntR family)
| Gene name | nagR |
| Synonyms | yvoA |
| Essential | no |
| Product | transcriptional regulator (GntR family) |
| Function | probably regulator of the putative nagA-nagB-yvoA operon |
| Gene expression levels in SubtiExpress: nagR | |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism, Murein recycling | |
| MW, pI | 27 kDa, 6.768 |
| Gene length, protein length | 729 bp, 243 aa |
| Immediate neighbours | nagB, yvnB |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
utilization of specific carbon sources, transcription factors and their control
This gene is a member of the following regulons
The NagR regulon:
The gene
Basic information
- Locus tag: BSU35030
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transcription repression of nagP and of the putative nagA-nagB-nagR operon in the absence of N-acetylglycosamine PubMed, weak repression of yflG PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information: K(D) for N-acetylglucosamine-6-phosphate: 1 mM PubMed
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- UniProt: O34817
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
Marcus Resch, Emile Schiltz, Fritz Titgemeyer, Yves A Muller
Insight into the induction mechanism of the GntR/HutC bacterial transcription regulator YvoA.
Nucleic Acids Res: 2010, 38(7);2485-97
[PubMed:20047956]
[WorldCat.org]
[DOI]
(I p)
Marcus Resch, Heide Marie Roth, Mathias Kottmair, Madhumati Sevvana, Ralph Bertram, Fritz Titgemeyer, Yves A Muller
Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of YvoA from Bacillus subtilis.
Acta Crystallogr Sect F Struct Biol Cryst Commun: 2009, 65(Pt 4);410-4
[PubMed:19342794]
[WorldCat.org]
[DOI]
(I p)
CongHui You, HongYan Lu, Agnieszka Sekowska, Gang Fang, YiPing Wang, Anne-Marie Gilles, Antoine Danchin
The two authentic methionine aminopeptidase genes are differentially expressed in Bacillus subtilis.
BMC Microbiol: 2005, 5;57
[PubMed:16207374]
[WorldCat.org]
[DOI]
(I e)
