Difference between revisions of "BceR"

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=References=
 
=References=
'''Additional publications:''' {{PubMed|21078927}}
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<pubmed>10094672,18394148,12890034,14651641, 21283517, 20606066, 17905982 </pubmed>
 
<pubmed>10094672,18394148,12890034,14651641, 21283517, 20606066, 17905982 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 09:05, 12 September 2012

  • Description: two-component response regulator, regulation of bceA-bceB in response to bacitracin, plectasin, mersacidin and actagardine

Gene name bceR
Synonyms ytsA
Essential no
Product two-component response regulator
Function resistance against toxic peptides
Gene expression levels in SubtiExpress: bceR
Interactions involving this protein in SubtInteract: BceR
MW, pI 26 kDa, 5.289
Gene length, protein length 693 bp, 231 aa
Immediate neighbours bceS, ytrF
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YtsA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
BceR expression.png















Categories containing this gene/protein

transcription factors and their control, resistance against toxins/ antibiotics, phosphoproteins

This gene is a member of the following regulons

The BceR regulon:

The gene

Basic information

  • Locus tag: BSU30400

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylated by BceS on an Asp residue
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Stéphanie Coumes-Florens, Céline Brochier-Armanet, Annick Guiseppi, François Denizot, Maryline Foglino
A new highly conserved antibiotic sensing/resistance pathway in firmicutes involves an ABC transporter interplaying with a signal transduction system.
PLoS One: 2011, 6(1);e15951
[PubMed:21283517] [WorldCat.org] [DOI] (I e)

Jing Ouyang, Xiao-Lin Tian, Jennifer Versey, Alexander Wishart, Yung-Hua Li
The BceABRS four-component system regulates the bacitracin-induced cell envelope stress response in Streptococcus mutans.
Antimicrob Agents Chemother: 2010, 54(9);3895-906
[PubMed:20606066] [WorldCat.org] [DOI] (I p)

Eva Rietkötter, Diana Hoyer, Thorsten Mascher
Bacitracin sensing in Bacillus subtilis.
Mol Microbiol: 2008, 68(3);768-85
[PubMed:18394148] [WorldCat.org] [DOI] (I p)

Remi Bernard, Annick Guiseppi, Marc Chippaux, Maryline Foglino, François Denizot
Resistance to bacitracin in Bacillus subtilis: unexpected requirement of the BceAB ABC transporter in the control of expression of its own structural genes.
J Bacteriol: 2007, 189(23);8636-42
[PubMed:17905982] [WorldCat.org] [DOI] (I p)

Thorsten Mascher, Neil G Margulis, Tao Wang, Rick W Ye, John D Helmann
Cell wall stress responses in Bacillus subtilis: the regulatory network of the bacitracin stimulon.
Mol Microbiol: 2003, 50(5);1591-604
[PubMed:14651641] [WorldCat.org] [DOI] (P p)

Reiko Ohki, Giyanto, Kozue Tateno, Waka Masuyama, Shigeki Moriya, Kazuo Kobayashi, Naotake Ogasawara
The BceRS two-component regulatory system induces expression of the bacitracin transporter, BceAB, in Bacillus subtilis.
Mol Microbiol: 2003, 49(4);1135-44
[PubMed:12890034] [WorldCat.org] [DOI] (P p)

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)