Difference between revisions of "AbnA"

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= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[AraR regulon]]}}
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{{SubtiWiki regulon|[[AraR regulon]]}},
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{{SubtiWiki regulon|[[CcpA regulon]]}}
  
 
=The gene=
 
=The gene=
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=== Additional information===
 
=== Additional information===
 
 
  
  
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:''' ''[[abnA]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/14973026 PubMed]
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* '''Operon:''' ''[[abnA]]'' {{PubMed|14973026}}
  
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=abnA_2949053_2950024_-1 abnA] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=abnA_2949053_2950024_-1 abnA] {{PubMed|22383849}}
  
* '''Sigma factor:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/14973026 PubMed]
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* '''Sigma factor:''' [[SigA]] {{PubMed|14973026}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
** repressed in the absence of arabinose ([[AraR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/14973026 PubMed]
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** repressed in the absence of arabinose ([[AraR]]) {{PubMed|14973026}}
 
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** subject to carbon catabolite repression ([[CcpA]]) {{PubMed|22900538}}
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
** [[AraR]]:  transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/14973026 PubMed]
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** [[AraR]]:  transcription repression {{PubMed|14973026}}
 +
** [[CcpA]]: transcription repression {{PubMed|22900538}}
  
 
* '''Additional information:''' the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed]
 
* '''Additional information:''' the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed]
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=References=
 
=References=
  
<pubmed>15556708,14973026,12884008,,14973026,18957862, </pubmed>
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<pubmed>15556708,14973026,12884008,22900538,14973026,18957862, </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 15:24, 21 August 2012

  • Description: endo-1,5-alpha-L-arabinosidase

Gene name abnA
Synonyms
Essential no
Product endo-1,5-alpha-L-arabinosidase
Function arabinan degradation
Gene expression levels in SubtiExpress: abnA
MW, pI 34 kDa, 8.618
Gene length, protein length 939 bp, 313 aa
Immediate neighbours araA, ysdC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
AbnA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
AbnA expression.png

















Categories containing this gene/protein

utilization of specific carbon sources

This gene is a member of the following regulons

AraR regulon, CcpA regulon

The gene

Basic information

  • Locus tag: BSU28810

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Endohydrolysis of (1->5)-alpha-arabinofuranosidic linkages in (1->5)-arabinans (according to Swiss-Prot)
  • Protein family: glycosyl hydrolase 43 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • repressed in the absence of arabinose (AraR) PubMed
    • subject to carbon catabolite repression (CcpA) PubMed
  • Regulatory mechanism:
  • Additional information: the mRNA is very stable (half-life > 15 min) PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References