Difference between revisions of "YqeH"
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|style="background:#ABCDEF;" align="center"|'''Function''' || ribosome assembly | |style="background:#ABCDEF;" align="center"|'''Function''' || ribosome assembly | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25670 yqeH] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 40 kDa, 6.009 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 40 kDa, 6.009 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[aroD]]'', ''[[yqeG]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[aroD]]'', ''[[yqeG]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU25670 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU25670 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU25670 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yqeH_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yqeH_context.gif]] | ||
Revision as of 13:21, 13 May 2013
- Description: assembly/ stability of the 30S subunit of the ribosome, assembly of the 70S ribosome
| Gene name | yqeH |
| Synonyms | |
| Essential | yes PubMed |
| Product | GTPase |
| Function | ribosome assembly |
| Gene expression levels in SubtiExpress: yqeH | |
| MW, pI | 40 kDa, 6.009 |
| Gene length, protein length | 1098 bp, 366 aa |
| Immediate neighbours | aroD, yqeG |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
translation, essential genes, GTP-binding proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU25670
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Binds and hydrolyzes GTP and readily exchanges GDP for GTP
- Protein family: Era/Obg family
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 3EC1 (Geobacillus stearothermophilus)
- UniProt: P54453
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Naotake Ogasawara, Nara, Japan
Your additional remarks
References
Reviews
Natalie Verstraeten, Maarten Fauvart, Wim Versées, Jan Michiels
The universally conserved prokaryotic GTPases.
Microbiol Mol Biol Rev: 2011, 75(3);507-42, second and third pages of table of contents
[PubMed:21885683]
[WorldCat.org]
[DOI]
(I p)
Robert A Britton
Role of GTPases in bacterial ribosome assembly.
Annu Rev Microbiol: 2009, 63;155-76
[PubMed:19575570]
[WorldCat.org]
[DOI]
(I p)
Original publications
Baskaran Anand, Parag Surana, Balaji Prakash
Deciphering the catalytic machinery in 30S ribosome assembly GTPase YqeH.
PLoS One: 2010, 5(4);e9944
[PubMed:20376346]
[WorldCat.org]
[DOI]
(I e)
Baskaran Anand, Parag Surana, Sagar Bhogaraju, Sushmita Pahari, Balaji Prakash
Circularly permuted GTPase YqeH binds 30S ribosomal subunit: Implications for its role in ribosome assembly.
Biochem Biophys Res Commun: 2009, 386(4);602-6
[PubMed:19540197]
[WorldCat.org]
[DOI]
(I p)
Pek Chin Loh, Takuya Morimoto, Yoshitaka Matsuo, Taku Oshima, Naotake Ogasawara
The GTP-binding protein YqeH participates in biogenesis of the 30S ribosome subunit in Bacillus subtilis.
Genes Genet Syst: 2007, 82(4);281-9
[PubMed:17895579]
[WorldCat.org]
[DOI]
(P p)
William C Uicker, Laura Schaefer, Mark Koenigsknecht, Robert A Britton
The essential GTPase YqeH is required for proper ribosome assembly in Bacillus subtilis.
J Bacteriol: 2007, 189(7);2926-9
[PubMed:17237168]
[WorldCat.org]
[DOI]
(P p)
Takuya Morimoto, Pek Chin Loh, Tomohiro Hirai, Kei Asai, Kazuo Kobayashi, Shigeki Moriya, Naotake Ogasawara
Six GTP-binding proteins of the Era/Obg family are essential for cell growth in Bacillus subtilis.
Microbiology (Reading): 2002, 148(Pt 11);3539-3552
[PubMed:12427945]
[WorldCat.org]
[DOI]
(P p)
