Difference between revisions of "YqeL"

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* '''Description:''' unknown <br/><br/>
+
* '''Description:''' ribosomal silencing factor <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
+
|style="background:#ABCDEF;" align="center"| '''Product''' || ribosomal silencing factor
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
+
|style="background:#ABCDEF;" align="center"|'''Function''' || [[translation]]
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU25620 yqeL]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU25620 yqeL]
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<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
 
 
 
<br/><br/>
 
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= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[proteins of unknown function]]}}
+
{{SubtiWiki category|[[translation]]}}
  
 
= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
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=== Additional information===
 
=== Additional information===
 
 
  
  
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* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
 +
** silences translation by binding to the L14 protein of the large ribosomal subunit and, as a consequence, impairs subunit joining  {{PubMed|22829778}}
  
 
* '''Protein family:''' Iojap family (according to Swiss-Prot)
 
* '''Protein family:''' Iojap family (according to Swiss-Prot)
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:'''
+
* '''[[SubtInteract|Interactions]]:'''
 +
** [[RplN]]-[[YqeL]] {{PubMed|22829778}}, the interaction serves to silence [[translation]] {{PubMed|22829778}}
  
* '''Localization:'''
+
* '''[[Localization]]:'''
  
 
=== Database entries ===
 
=== Database entries ===
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=References=
 
=References=
 
+
<pubmed> 22829778 </pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 17:19, 28 August 2012

  • Description: ribosomal silencing factor

Gene name yqeL
Synonyms
Essential no
Product ribosomal silencing factor
Function translation
Gene expression levels in SubtiExpress: yqeL
MW, pI 13 kDa, 4.367
Gene length, protein length 354 bp, 118 aa
Immediate neighbours yqeM, yqeK
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YqeL context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YqeL expression.png















Categories containing this gene/protein

translation

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU25620

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • silences translation by binding to the L14 protein of the large ribosomal subunit and, as a consequence, impairs subunit joining PubMed
  • Protein family: Iojap family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Roman Häuser, Markus Pech, Jaroslaw Kijek, Hiroshi Yamamoto, Björn Titz, Florian Naeve, Andrey Tovchigrechko, Kaori Yamamoto, Witold Szaflarski, Nono Takeuchi, Thorsten Stellberger, Markus E Diefenbacher, Knud H Nierhaus, Peter Uetz
RsfA (YbeB) proteins are conserved ribosomal silencing factors.
PLoS Genet: 2012, 8(7);e1002815
[PubMed:22829778] [WorldCat.org] [DOI] (I p)