YjbC

• Description: general stress protein, required for survival of salt stress
  
  

Gene name	yjbC
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: yjbC
MW, pI	22 kDa, 5.14
Gene length, protein length	576 bp, 192 aa
Immediate neighbours	yjbB, spx
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

general stress proteins (controlled by SigB), cell envelope stress proteins (controlled by SigM, V, W, X, Y)

This gene is a member of the following regulons

PerR regulon, SigB regulon, SigM regulon, SigW regulon, SigX regulon

The gene

Basic information

• Locus tag: BSU11490

Phenotypes of a mutant

strongly impaired survival of salt stress PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O31601

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yjbC-spx PubMed

• Expression browser: yjbC PubMed

• Sigma factor: SigW, SigB, SigX, PubMed, SigM PubMed

• Regulation:
  • induced by stress (SigB) PubMed
  • transcription is represed by YodB PubMed
  • repressed in the absence of hydrogen peroxide (PerR) PubMed

• Regulatory mechanism: transcription repression
  • PerR: transcription repression PubMed

• Additional information:
  • the mRNA is substantially stabilized upon depletion of RNase Y PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J  
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y. 
Mol Microbiol. 2011 81(6): 1459-1473. 
PubMed:21815947