Difference between revisions of "YcbC"

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* '''Description:''' 5-dehydro-4-deoxyglucarate dehydratase <br/><br/>
  
 
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|style="background:#ABCDEF;" align="center"|'''Function''' || utilization of D-glucarate/galactarate
 
|style="background:#ABCDEF;" align="center"|'''Function''' || utilization of D-glucarate/galactarate
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU02460 ycbC]
 
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 5.375   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 5.375   
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|colspan="2" | '''Genetic context''' <br/> [[Image:ycbC_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ycbC_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ycbC_267890_268816_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:ycbC_expression.png|500px]]
 
 
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* '''Operon:''' ''[[ycbC]]-[[ycbD]]-[[ycbE]]-[[ycbF]]-[[ycbG]]-[[ycbH]]-[[ycbJ]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/12044674 PubMed]
 
* '''Operon:''' ''[[ycbC]]-[[ycbD]]-[[ycbE]]-[[ycbF]]-[[ycbG]]-[[ycbH]]-[[ycbJ]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/12044674 PubMed]
  
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ycbC_267890_268816_1 ycbC] {{PubMed|22383849}}
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* '''[[Sigma factor]]:'''  
 
 
* '''Sigma factor:'''  
 
  
 
* '''Regulation:''' induced by D-glucarate/galactarate ([[YcbG]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12044674 PubMed]
 
* '''Regulation:''' induced by D-glucarate/galactarate ([[YcbG]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12044674 PubMed]

Revision as of 10:45, 7 August 2012

  • Description: 5-dehydro-4-deoxyglucarate dehydratase

Gene name ycbC
Synonyms
Essential no
Product 5-dehydro-4-deoxyglucarate dehydratase
Function utilization of D-glucarate/galactarate
MW, pI 33 kDa, 5.375
Gene length, protein length 924 bp, 308 aa
Immediate neighbours glnL, ycbD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YcbC context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

utilization of specific carbon sources

This gene is a member of the following regulons

YcbG regulon

The gene

Basic information

  • Locus tag: BSU02460

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 5-dehydro-4-deoxy-D-glucarate = 2,5-dioxopentanoate + H2O + CO2 (according to Swiss-Prot)
  • Protein family: DHDPS family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation: induced by D-glucarate/galactarate (YcbG) PubMed
  • Regulatory mechanism: YcbG: transcription repression PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Shigeo Hosoya, Kunio Yamane, Michio Takeuchi, Tsutomu Sato
Identification and characterization of the Bacillus subtilis D-glucarate/galactarate utilization operon ycbCDEFGHJ.
FEMS Microbiol Lett: 2002, 210(2);193-9
[PubMed:12044674] [WorldCat.org] [DOI] (P p)