Difference between revisions of "YabM"
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| − | + | * '''Description:''' may function in a previously observed alternate pathway for peptidoglycan strand synthesis <br/><br/> | |
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|style="background:#ABCDEF;" align="center"|'''Function''' || alternate pathway for peptidoglycan strand synthesis | |style="background:#ABCDEF;" align="center"|'''Function''' || alternate pathway for peptidoglycan strand synthesis | ||
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 57 kDa, 9.623 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 57 kDa, 9.623 | ||
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|colspan="2" | '''Genetic context''' <br/> [[Image:yabM_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yabM_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
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__TOC__ | __TOC__ | ||
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* '''Operon:''' ''[[yabM]]-[[yabN]]-[[yabO]]-[[yabP]]-[[yabQ]]-[[divIC]]-[[yabR]]'' {{PubMed|11283287}} | * '''Operon:''' ''[[yabM]]-[[yabN]]-[[yabO]]-[[yabP]]-[[yabQ]]-[[divIC]]-[[yabR]]'' {{PubMed|11283287}} | ||
| − | * | + | * '''[[Sigma factor]]:''' |
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* '''Regulation:''' | * '''Regulation:''' | ||
Revision as of 10:18, 7 August 2012
- Description: may function in a previously observed alternate pathway for peptidoglycan strand synthesis
| Gene name | yabM |
| Synonyms | |
| Essential | no |
| Product | unknown |
| Function | alternate pathway for peptidoglycan strand synthesis |
| MW, pI | 57 kDa, 9.623 |
| Gene length, protein length | 1596 bp, 532 aa |
| Immediate neighbours | spoVT, yabN |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
cell wall synthesis, biosynthesis of cell wall components, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00570
Phenotypes of a mutant
Mutants lacking YabM exhibit sensitivity to moenomycin, an antibiotic that blocks peptidoglycan polymerization by class A penicillin-binding proteins. PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: may function in a previously observed alternate pathway for peptidoglycan strand synthesis PubMed
- Protein family: polysaccharide synthase family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P37555
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Allison Fay, Jonathan Dworkin
Bacillus subtilis homologs of MviN (MurJ), the putative Escherichia coli lipid II flippase, are not essential for growth.
J Bacteriol: 2009, 191(19);6020-8
[PubMed:19666716]
[WorldCat.org]
[DOI]
(I p)
Pradeep Vasudevan, Jessica McElligott, Christa Attkisson, Michael Betteken, David L Popham
Homologues of the Bacillus subtilis SpoVB protein are involved in cell wall metabolism.
J Bacteriol: 2009, 191(19);6012-9
[PubMed:19648239]
[WorldCat.org]
[DOI]
(I p)
Kei Asai, Hiromu Takamatsu, Megumi Iwano, Takeko Kodama, Kazuhito Watabe, Naotake Ogasawara
The Bacillus subtilis yabQ gene is essential for formation of the spore cortex.
Microbiology (Reading): 2001, 147(Pt 4);919-927
[PubMed:11283287]
[WorldCat.org]
[DOI]
(P p)
