Difference between revisions of "AdeR"
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || transcription activator (PucR family) | + | |style="background:#ABCDEF;" align="center"| '''Product''' || transcription activator ([[PucR family]]) |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || control of ''[[ald]]'' expression | |style="background:#ABCDEF;" align="center"|'''Function''' || control of ''[[ald]]'' expression | ||
| Line 68: | Line 68: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' transcription activation of ''[[ald]]'' gene expression in the presence of alanine {{PubMed|22797752}} |
| − | * '''Protein family:''' | + | * '''Protein family:''' [[PucR family]] |
* '''Paralogous protein(s):''' | * '''Paralogous protein(s):''' | ||
| Line 135: | Line 135: | ||
=References= | =References= | ||
| − | <pubmed> 8226620 20509597 </pubmed> | + | <pubmed> 8226620 20509597 22797752 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 15:36, 17 July 2012
- Description: transcription activator (PucR family) for ald gene expression
| Gene name | yukF |
| Synonyms | |
| Essential | no |
| Product | transcription activator (PucR family) |
| Function | control of ald expression |
| MW, pI | 50 kDa, 8.147 |
| Gene length, protein length | 1302 bp, 434 aa |
| Immediate neighbours | yukE, ald |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
transcription factors and their control, utilization of amino acids
This gene is a member of the following regulons
The AdeR regulon
The gene
Basic information
- Locus tag: BSU31920
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transcription activation of ald gene expression in the presence of alanine PubMed
- Protein family: PucR family
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylated on Ser-395 PubMed
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P71073
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: yukF PubMed
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Ta-Hui Lin, Guei-Tsung Wei, Chien-Chen Su, Gwo-Chyuan Shaw
AdeR, a PucR-type transcription factor, activates expression of L-alanine dehydrogenase and is required for sporulation of Bacillus subtilis.
J Bacteriol: 2012, 194(18);4995-5001
[PubMed:22797752]
[WorldCat.org]
[DOI]
(I p)
Boumediene Soufi, Chanchal Kumar, Florian Gnad, Matthias Mann, Ivan Mijakovic, Boris Macek
Stable isotope labeling by amino acids in cell culture (SILAC) applied to quantitative proteomics of Bacillus subtilis.
J Proteome Res: 2010, 9(7);3638-46
[PubMed:20509597]
[WorldCat.org]
[DOI]
(I p)
K J Siranosian, K Ireton, A D Grossman
Alanine dehydrogenase (ald) is required for normal sporulation in Bacillus subtilis.
J Bacteriol: 1993, 175(21);6789-96
[PubMed:8226620]
[WorldCat.org]
[DOI]
(P p)
