Difference between revisions of "RefZ"
| Line 1: | Line 1: | ||
| − | * '''Description:''' | + | * '''Description:''' regulator of [[FtsZ]], facilitates switch from medial to polar [[FtsZ]] ring placement during [[sporulation]] <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || regulator of [[FtsZ]] |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || relocalization of the [[FtsZ]] ring |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 24 kDa, 6.706 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 24 kDa, 6.706 | ||
| Line 40: | Line 40: | ||
= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
| − | {{SubtiWiki category|[[ | + | {{SubtiWiki category|[[cell division]]}}, |
| + | {{SubtiWiki category|[[sporulation/ other]]}} | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| Line 62: | Line 63: | ||
=== Additional information=== | === Additional information=== | ||
| − | |||
| − | |||
| Line 70: | Line 69: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' facilitates switch from medial to polar [[FtsZ]] ring placement during [[sporulation]] {{PubMed|22730127}} |
* '''Protein family:''' | * '''Protein family:''' | ||
| Line 88: | Line 87: | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' | + | * '''[[SubtInteract|Interactions]]:''' |
| − | * '''Localization:''' | + | * '''[[Localization]]:''' |
| + | ** polar foci {{PubMed|22730127}} | ||
=== Database entries === | === Database entries === | ||
| Line 114: | Line 114: | ||
* '''Regulation:''' | * '''Regulation:''' | ||
** repressed by glucose (3.1-fold) ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed] | ** repressed by glucose (3.1-fold) ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed] | ||
| − | ** | + | ** induced early during [[sporulation]] ([[Spo0A]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647 PubMed] |
** expressed under conditions of phosphate limitation ([[PhoP]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/14762014 PubMed] | ** expressed under conditions of phosphate limitation ([[PhoP]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/14762014 PubMed] | ||
Revision as of 15:58, 6 July 2012
- Description: regulator of FtsZ, facilitates switch from medial to polar FtsZ ring placement during sporulation
| Gene name | yttP |
| Synonyms | |
| Essential | no |
| Product | regulator of FtsZ |
| Function | relocalization of the FtsZ ring |
| MW, pI | 24 kDa, 6.706 |
| Gene length, protein length | 621 bp, 207 aa |
| Immediate neighbours | hisJ, ytsP |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
cell division, sporulation/ other
This gene is a member of the following regulons
CcpA regulon, PhoP regulon, Spo0A regulon
The gene
Basic information
- Locus tag: BSU29630
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: facilitates switch from medial to polar FtsZ ring placement during sporulation PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- polar foci PubMed
Database entries
- Structure:
- UniProt: O34970
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: yttP (according to DBTBS)
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Jennifer K Wagner-Herman, Remi Bernard, Roisin Dunne, Alexandre W Bisson-Filho, Krithika Kumar, Trang Nguyen, Lawrence Mulcahy, John Koullias, Frederico J Gueiros-Filho, David Z Rudner
RefZ facilitates the switch from medial to polar division during spore formation in Bacillus subtilis.
J Bacteriol: 2012, 194(17);4608-18
[PubMed:22730127]
[WorldCat.org]
[DOI]
(I p)
Zoltán Prágai, Nicholas E E Allenby, Nicola O'Connor, Sarah Dubrac, Georges Rapoport, Tarek Msadek, Colin R Harwood
Transcriptional regulation of the phoPR operon in Bacillus subtilis.
J Bacteriol: 2004, 186(4);1182-90
[PubMed:14762014]
[WorldCat.org]
[DOI]
(P p)
Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647]
[WorldCat.org]
[DOI]
(P p)
Hans-Matti Blencke, Georg Homuth, Holger Ludwig, Ulrike Mäder, Michael Hecker, Jörg Stülke
Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways.
Metab Eng: 2003, 5(2);133-49
[PubMed:12850135]
[WorldCat.org]
[DOI]
(P p)
