GlnM

• Description: glutamine ABC transporter (membrane protein)
  
  

Gene name	glnM
Synonyms
Essential	no
Product	glutamine ABC transporter (membrane protein)
Function	glutamine uptake
Interactions involving this protein in SubtInteract: GlnM
Metabolic function and regulation of this protein in SubtiPathways: Ammonium/ glutamate
MW, pI	23 kDa, 8.416
Gene length, protein length	648 bp, 216 aa
Immediate neighbours	glnH, glnP
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, biosynthesis/ acquisition of amino acids, glutamate metabolism, utilization of amino acids, membrane proteins, sporulation proteins

This gene is a member of the following regulons

SigE regulon, TnrA regulon

The gene

Basic information

• Locus tag: BSU27450

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • GlnQ-(GlnM-GlnP)-GlnH PubMed

• Localization: cell membrane PubMed

Database entries

• Structure:

• UniProt: O34671

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: glnQ-glnH-glnM-glnP PubMed

• Expression browser: glnM PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • expressed in the absence of good nitrogen sources (glutamine or ammonium) (TnrA) PubMed
  • expressed during sporulation (SigE) PubMed

• Regulatory mechanism:
  • TnrA: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190] [WorldCat.org] [DOI] (P p)

Ken-ichi Yoshida, Hirotake Yamaguchi, Masaki Kinehara, Yo-hei Ohki, Yoshiko Nakaura, Yasutaro Fujita
Identification of additional TnrA-regulated genes of Bacillus subtilis associated with a TnrA box.
Mol Microbiol: 2003, 49(1);157-65
[PubMed:12823818] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)