Difference between revisions of "SodA"

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|style="background:#ABCDEF;" align="center"|'''Function''' || detoxification of oxygen radicals  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || detoxification of oxygen radicals  
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU25020 sodA]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 22 kDa, 5.203   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 22 kDa, 5.203   

Revision as of 13:51, 7 August 2012

  • Description: superoxide dismutase, general stress protein, important for survival of ethanol stress and at low temperatures

Gene name sodA
Synonyms yqgD
Essential no
Product superoxide dismutase
Function detoxification of oxygen radicals
Gene expression levels in SubtiExpress: sodA
MW, pI 22 kDa, 5.203
Gene length, protein length 606 bp, 202 aa
Immediate neighbours yqgE, yqgC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SodA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SodA expression.png
























Categories containing this gene/protein

general stress proteins (controlled by SigB), resistance against oxidative and electrophile stress, membrane proteins, phosphoproteins

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

  • Locus tag: BSU25020

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 2 superoxide + 2 H+ = O2 + H2O2 (according to Swiss-Prot)
  • Protein family: iron/manganese superoxide dismutase family (according to Swiss-Prot)
  • Paralogous protein(s): SodF

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylation on Thr-34 AND Thr-70 PubMed
  • Cofactor(s): manganese
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulatory mechanism:
  • Additional information:
    • The mRNA has a long 5' leader region. This may indicate RNA-based regulation PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References