Difference between revisions of "CotM"

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= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[GerE regulon]]}},
+
{{SubtiWiki regulon|[[SigE regulon]]}},
{{SubtiWiki regulon|[[SigK regulon]]}}
+
{{SubtiWiki regulon|[[SigK regulon]]}},
 +
{{SubtiWiki regulon|[[GerE regulon]]}}
  
 
=The gene=
 
=The gene=
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* '''[[Localization]]:'''
 
* '''[[Localization]]:'''
 +
** spore coat {{PubMed|22171814}}
  
 
=== Database entries ===
 
=== Database entries ===
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cotM_1925655_1926047_-1 cotM] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cotM_1925655_1926047_-1 cotM] {{PubMed|22383849}}
  
* '''Sigma factor:''' [[SigK]] {{PubMed|9068633}}
+
* '''Sigma factor:''' [[SigE]] {{PubMed|15383836}}, [[SigK]] {{PubMed|9068633}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
** expressed late during sporulation in the mother cell ([[SigK]]) {{PubMed|9068633}}
+
** expressed during sporulation in the mother cell ([[SigE]], [[SigK]], [[GerE]]) {{PubMed|15383836,9068633}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
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=References=
 
=References=
  
<pubmed>11150673,9068633,20525796, </pubmed>
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<pubmed>11150673,9068633,20525796, 15383836 22171814</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 16:38, 29 July 2012

  • Description: spore coat protein (outer)

Gene name cotM
Synonyms yneL
Essential no
Product spore coat protein (outer)
Function resistance of the spore
MW, pI 15 kDa, 3.942
Gene length, protein length 390 bp, 130 aa
Immediate neighbours yneK, sspP
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
CotM context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CotM expression.png















Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

SigE regulon, SigK regulon, GerE regulon

The gene

Basic information

  • Locus tag: BSU17970

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Peter T McKenney, Patrick Eichenberger
Dynamics of spore coat morphogenesis in Bacillus subtilis.
Mol Microbiol: 2012, 83(2);245-60
[PubMed:22171814] [WorldCat.org] [DOI] (I p)

Irnov Irnov, Cynthia M Sharma, Jörg Vogel, Wade C Winkler
Identification of regulatory RNAs in Bacillus subtilis.
Nucleic Acids Res: 2010, 38(19);6637-51
[PubMed:20525796] [WorldCat.org] [DOI] (I p)

Patrick Eichenberger, Masaya Fujita, Shane T Jensen, Erin M Conlon, David Z Rudner, Stephanie T Wang, Caitlin Ferguson, Koki Haga, Tsutomu Sato, Jun S Liu, Richard Losick
The program of gene transcription for a single differentiating cell type during sporulation in Bacillus subtilis.
PLoS Biol: 2004, 2(10);e328
[PubMed:15383836] [WorldCat.org] [DOI] (I p)

S Reischl, S Thake, G Homuth, W Schumann
Transcriptional analysis of three Bacillus subtilis genes coding for proteins with the alpha-crystallin domain characteristic of small heat shock proteins.
FEMS Microbiol Lett: 2001, 194(1);99-103
[PubMed:11150673] [WorldCat.org] [DOI] (P p)

A O Henriques, B W Beall, C P Moran
CotM of Bacillus subtilis, a member of the alpha-crystallin family of stress proteins, is induced during development and participates in spore outer coat formation.
J Bacteriol: 1997, 179(6);1887-97
[PubMed:9068633] [WorldCat.org] [DOI] (P p)