Difference between revisions of "NsrR"
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|style="background:#ABCDEF;" align="center"|'''Function''' || repression of [[ResD]]-[[ResE]]-dependent genes in the absence of nitric oxide (NO) | |style="background:#ABCDEF;" align="center"|'''Function''' || repression of [[ResD]]-[[ResE]]-dependent genes in the absence of nitric oxide (NO) | ||
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| + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU09380 nsrR] | ||
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress], [http://subtiwiki.uni-goettingen.de/pathways/other_nitrogen_sources/index.html Alternative nitrogen sources]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress], [http://subtiwiki.uni-goettingen.de/pathways/other_nitrogen_sources/index.html Alternative nitrogen sources]''' | ||
Revision as of 16:16, 6 August 2012
| Gene name | nsrR |
| Synonyms | yhdE |
| Essential | no |
| Product | transcriptional repressor |
| Function | repression of ResD-ResE-dependent genes in the absence of nitric oxide (NO) |
| Gene expression levels in SubtiExpress: nsrR | |
| Metabolic function and regulation of this protein in SubtiPathways: Stress, Alternative nitrogen sources | |
| MW, pI | 16 kDa, 7.75 |
| Gene length, protein length | 438 bp, 146 aa |
| Immediate neighbours | lytF, ygxB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
transcription factors and their control, resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)
This gene is a member of the following regulons
The NsrR regulon
The gene
Basic information
- Locus tag: BSU09380
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s): [4Fe-4S] cluster, required for DNA-binding PubMed
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O07573
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: nsrR PubMed
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
The NsrR regulon
Sushma Kommineni, Amrita Lama, Benjamin Popescu, Michiko M Nakano
Global transcriptional control by NsrR in Bacillus subtilis.
J Bacteriol: 2012, 194(7);1679-88
[PubMed:22287527]
[WorldCat.org]
[DOI]
(I p)
Other original publications
Sushma Kommineni, Erik Yukl, Takahiro Hayashi, Jacob Delepine, Hao Geng, Pierre Moënne-Loccoz, Michiko M Nakano
Nitric oxide-sensitive and -insensitive interaction of Bacillus subtilis NsrR with a ResDE-controlled promoter.
Mol Microbiol: 2010, 78(5);1280-93
[PubMed:21091510]
[WorldCat.org]
[DOI]
(I p)
Annika Rogstam, Jonas T Larsson, Peter Kjelgaard, Claes von Wachenfeldt
Mechanisms of adaptation to nitrosative stress in Bacillus subtilis.
J Bacteriol: 2007, 189(8);3063-71
[PubMed:17293416]
[WorldCat.org]
[DOI]
(P p)
Michiko M Nakano, Hao Geng, Shunji Nakano, Kazuo Kobayashi
The nitric oxide-responsive regulator NsrR controls ResDE-dependent gene expression.
J Bacteriol: 2006, 188(16);5878-87
[PubMed:16885456]
[WorldCat.org]
[DOI]
(P p)
Additional publications: PubMed
