Difference between revisions of "SecE"

From SubtiWiki
Jump to: navigation, search
Line 28: Line 28:
 
|colspan="2" | '''Genetic context''' <br/> [[Image:secE_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:secE_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 +
|-
 +
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=secE_117532_117711_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:secE_expression.png|500px]]
 
|-
 
|-
 
|}
 
|}
  
 
__TOC__
 
__TOC__
 +
<br/><br/><br/><br/>
 +
<br/><br/><br/><br/>
 +
<br/><br/><br/><br/>
 +
<br/><br/><br/><br/>
 +
<br/><br/><br/><br/>
 +
  
 
<br/><br/>
 
<br/><br/>

Revision as of 12:46, 18 April 2012

  • Description: preprotein translocase subunit

Gene name secE
Synonyms
Essential yes PubMed
Product preprotein translocase subunit
Function protein secretion
Interactions involving this protein in SubtInteract: SecE
Metabolic function and regulation of this protein in SubtiPathways:
Protein secretion
MW, pI 6 kDa, 10.47
Gene length, protein length 177 bp, 59 aa
Immediate neighbours rpmGB, nusG
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SecE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SecE expression.png
























Categories containing this gene/protein

protein secretion, essential genes, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU01000

Phenotypes of a mutant

essential PubMed PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: secE/SEC61-gamma family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: transmembrane protein with a single TM domain
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

B. subtilis secE complements the secretion phenotype of a cold sensitive E. coli secE mutant.

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jochen Zimmer, Yunsun Nam, Tom A Rapoport
Structure of a complex of the ATPase SecA and the protein-translocation channel.
Nature: 2008, 455(7215);936-43
[PubMed:18923516] [WorldCat.org] [DOI] (I p)

S M Jeong, H Yoshikawa, H Takahashi
Isolation and characterization of the secE homologue gene of Bacillus subtilis.
Mol Microbiol: 1993, 10(1);133-42
[PubMed:7968510] [WorldCat.org] [DOI] (P p)