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<big>'''Paper of the month: March 2012'''</big>  
 
<big>'''Paper of the month: March 2012'''</big>  
* [http://www.ncbi.nlm.nih.gov/pubmed/22383848 Buescher ''et al''.] and [http://www.ncbi.nlm.nih.gov/pubmed/22383849 Nicholas ''et al''.] from the BaSysBio consortium diected by [[Philippe Noirot]] studied the dynamic metabolic and transcriptional responses of ''B. subtilis'' to changes of the growth conditions. One of the major issues is the adaptation of the cells upon a nutrient switch from glucose to malate and ''vice versa''. Importantly, the study by [http://www.ncbi.nlm.nih.gov/pubmed/22383849 Nicholas ''et al''.] provides an analysis of gene expression at 104 different conditions as revealed by tiling arrays.
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* [http://www.ncbi.nlm.nih.gov/pubmed/22383848 Buescher ''et al''.] and [http://www.ncbi.nlm.nih.gov/pubmed/22383849 Nicolas ''et al''.] from the BaSysBio consortium diected by [[Philippe Noirot]] studied the dynamic metabolic and transcriptional responses of ''B. subtilis'' to changes of the growth conditions. One of the major issues is the adaptation of the cells upon a nutrient switch from glucose to malate and ''vice versa''. Importantly, the study by [http://www.ncbi.nlm.nih.gov/pubmed/22383849 Nicholas ''et al''.] provides an analysis of gene expression at 104 different conditions as revealed by tiling arrays.
 
* '''Relevant ''Subti''Wiki pages:'''  [[Philippe Noirot]], [[Michael Hecker]], [[Uwe Völker]], [[Philippe Bessières]], [[Uwe Sauer]], [[Stephane Aymerich]], [[Tony Wilkinson]], [[metabolism]], [[transcription]], [[CcpA]], [[Sigma factors]], [[ncRNA|sRNAs]], [[Rho]]
 
* '''Relevant ''Subti''Wiki pages:'''  [[Philippe Noirot]], [[Michael Hecker]], [[Uwe Völker]], [[Philippe Bessières]], [[Uwe Sauer]], [[Stephane Aymerich]], [[Tony Wilkinson]], [[metabolism]], [[transcription]], [[CcpA]], [[Sigma factors]], [[ncRNA|sRNAs]], [[Rho]]
 
<pubmed>22383848 22383849</pubmed>
 
<pubmed>22383848 22383849</pubmed>

Revision as of 09:47, 5 March 2012

Welcome to SubtiWiki! - Bacillus subtilis annotation the "wiki" way!

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Contact: General Microbiology, University of Göttingen, send mail


Upcoming events:

  • April 16 - 19, 2012: The 5th European Spore Conference will take place in London, UK. contact, conference website
  • April 24 - 25, 2012: The BACELL meeting 2012 will be organized by Kevin Devine in Dublin, Ireland. contact, The deadline for registration is approaching!

Past conferences


New: Subtiwiki is now on Facebook - please give it a +1!


Now online: A description of SubtiWiki, SubtiPathways, and SubtInteract in the 2012 Database issue of Nucleic Acids Research



Paper of the month: March 2012

Pierre Nicolas, Ulrike Mäder, Etienne Dervyn, Tatiana Rochat, Aurélie Leduc, Nathalie Pigeonneau, Elena Bidnenko, Elodie Marchadier, Mark Hoebeke, Stéphane Aymerich, Dörte Becher, Paola Bisicchia, Eric Botella, Olivier Delumeau, Geoff Doherty, Emma L Denham, Mark J Fogg, Vincent Fromion, Anne Goelzer, Annette Hansen, Elisabeth Härtig, Colin R Harwood, Georg Homuth, Hanne Jarmer, Matthieu Jules, Edda Klipp, Ludovic Le Chat, François Lecointe, Peter Lewis, Wolfram Liebermeister, Anika March, Ruben A T Mars, Priyanka Nannapaneni, David Noone, Susanne Pohl, Bernd Rinn, Frank Rügheimer, Praveen K Sappa, Franck Samson, Marc Schaffer, Benno Schwikowski, Leif Steil, Jörg Stülke, Thomas Wiegert, Kevin M Devine, Anthony J Wilkinson, Jan Maarten van Dijl, Michael Hecker, Uwe Völker, Philippe Bessières, Philippe Noirot
Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis.
Science: 2012, 335(6072);1103-6
[PubMed:22383849] [WorldCat.org] [DOI] (I p)

Joerg Martin Buescher, Wolfram Liebermeister, Matthieu Jules, Markus Uhr, Jan Muntel, Eric Botella, Bernd Hessling, Roelco Jacobus Kleijn, Ludovic Le Chat, François Lecointe, Ulrike Mäder, Pierre Nicolas, Sjouke Piersma, Frank Rügheimer, Dörte Becher, Philippe Bessieres, Elena Bidnenko, Emma L Denham, Etienne Dervyn, Kevin M Devine, Geoff Doherty, Samuel Drulhe, Liza Felicori, Mark J Fogg, Anne Goelzer, Annette Hansen, Colin R Harwood, Michael Hecker, Sebastian Hubner, Claus Hultschig, Hanne Jarmer, Edda Klipp, Aurélie Leduc, Peter Lewis, Frank Molina, Philippe Noirot, Sabine Peres, Nathalie Pigeonneau, Susanne Pohl, Simon Rasmussen, Bernd Rinn, Marc Schaffer, Julian Schnidder, Benno Schwikowski, Jan Maarten Van Dijl, Patrick Veiga, Sean Walsh, Anthony J Wilkinson, Jörg Stelling, Stéphane Aymerich, Uwe Sauer
Global network reorganization during dynamic adaptations of Bacillus subtilis metabolism.
Science: 2012, 335(6072);1099-103
[PubMed:22383848] [WorldCat.org] [DOI] (I p)

  • A comment on these papers:

Guilhem Chalancon, Kai Kruse, M Madan Babu
Cell biology. Reconfiguring regulation.
Science: 2012, 335(6072);1050-1
[PubMed:22383834] [WorldCat.org] [DOI] (I p)



New procedure for account creation:

  • Due to massive spam attacks, we had to change our policy for the creation of accounts. If you want to create an account, just send me a mail. We will create the account for you as quickly as possible, then you can change your password. This does not affect existing accounts, which remain active.
  • Please remember that all members of the Bacillus community are invited to create accounts and to contribute to SubtiWiki!



News in SubtiWiki:


Genes (examples) Additional pages
spo0A SubtiPathways
glnA Lists of genes, proteins and RNAs
rny Categories
psdA Regulons
pckA methods
dnaA metabolism
rnpA protein-protein interactions
sigB genome-wide analyses
ptkA list of plasmids
mreC labs working on Bacillus
ccpA the people behind SubtiWiki
sr1 template


Publications describing SubtiWiki and SubtiPathways:

Lope A Flórez, Sebastian F Roppel, Arne G Schmeisky, Christoph R Lammers, Jörg Stülke
A community-curated consensual annotation that is continuously updated: the Bacillus subtilis centred wiki SubtiWiki.
Database (Oxford): 2009, 2009;bap012
[PubMed:20157485] [WorldCat.org] [DOI] (I p)

Christoph R Lammers, Lope A Flórez, Arne G Schmeisky, Sebastian F Roppel, Ulrike Mäder, Leendert Hamoen, Jörg Stülke
Connecting parts with processes: SubtiWiki and SubtiPathways integrate gene and pathway annotation for Bacillus subtilis.
Microbiology (Reading): 2010, 156(Pt 3);849-859
[PubMed:19959575] [WorldCat.org] [DOI] (I p)