YobK

• Description: antitoxin
  
  

Gene name	yobK
Synonyms
Essential	no
Product	antitoxin
Function	inhibition of the cytotoxic activity of YobL
Interactions involving this protein in SubtInteract: YobK
MW, pI	17 kDa, 3.97
Gene length, protein length	456 bp, 152 aa
Immediate neighbours	yobJ, yobL
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

toxins, antitoxins and immunity against toxins, membrane proteins,

The gene

Basic information

• Locus tag: BSU18990

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YobL-YobK PubMed

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure: 2PRV

• UniProt: O34596

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: yobK PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Laura E Holberger, Fernando Garza-Sánchez, James Lamoureux, David A Low, Christopher S Hayes
A novel family of toxin/antitoxin proteins in Bacillus species.
FEBS Lett: 2012, 586(2);132-6
[PubMed:22200572] [WorldCat.org] [DOI] (I p)