ZapA

• Description: positive modulator of FtsZ Z ring assembly and stability
  
  

Gene name	zapA
Synonyms	yshA
Essential	no
Product	Z-ring-associated protein
Function	control of Z-ring formation
Interactions involving this protein in SubtInteract: ZapA
MW, pI	9 kDa, 7.17
Gene length, protein length	255 bp, 85 aa
Immediate neighbours	yshB, rnhC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

cell division, membrane proteins

The gene

Basic information

• Locus tag: BSU28610

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: Type 2 subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • forms a dimer through its extensive coiled-coil region, FtsZ-ZapA PubMed

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P94542

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: zapA-yshB PubMed

• Expression browser: zapA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Marc Bramkamp, Suey van Baarle
Division site selection in rod-shaped bacteria.
Curr Opin Microbiol: 2009, 12(6);683-8
[PubMed:19884039] [WorldCat.org] [DOI] (I p)

David W Adams, Jeff Errington
Bacterial cell division: assembly, maintenance and disassembly of the Z ring.
Nat Rev Microbiol: 2009, 7(9);642-53
[PubMed:19680248] [WorldCat.org] [DOI] (I p)