YrhH

• Description: similar to methyltransferase
  
  

Gene name	yrhH
Synonyms
Essential	no
Product	unknown
Function	unknown
MW, pI	20 kDa, 10.159
Gene length, protein length	540 bp, 180 aa
Immediate neighbours	fatR, yrzI
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

cell envelope stress proteins (controlled by SigM, V, W, X, Y), poorly characterized/ putative enzymes

This gene is a member of the following regulons

SigM regulon, SigW regulon, SigX regulon

The gene

Basic information

• Locus tag: BSU27180

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: methyltransferase superfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O05400

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:
  • yrhH PubMed
  • yrhH-fatR-yrhJ PubMed

• Sigma factor: SigW PubMed, SigM PubMed, SigX PubMed

• Regulation:
  • Expressed under stress conditions (SigW, SigX) PubMed
  • expression is reduced in a SigV mutant PubMed

• Regulatory mechanism:

• Additional information:
  • the mRNA is substantially stabilized upon depletion of RNase Y PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J  
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y. 
Mol Microbiol. 2011 81(6): 1459-1473. 
PubMed:21815947

Warawan Eiamphungporn, John D Helmann
The Bacillus subtilis sigma(M) regulon and its contribution to cell envelope stress responses.
Mol Microbiol: 2008, 67(4);830-48
[PubMed:18179421] [WorldCat.org] [DOI] (P p)

X Huang, K L Fredrick, J D Helmann
Promoter recognition by Bacillus subtilis sigmaW: autoregulation and partial overlap with the sigmaX regulon.
J Bacteriol: 1998, 180(15);3765-70
[PubMed:9683469] [WorldCat.org] [DOI] (P p)