Difference between revisions of "RapA"

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* '''Locus tag:''' BSU12430
 
* '''Locus tag:''' BSU12430
 
[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rapA_1315869_1317005_1 Expression]
 
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===

Revision as of 12:41, 26 January 2012

Gene name rapA
Synonyms gsiAA, spo0L
Essential no
Product response regulator aspartate phosphatase
Function control of sporulation initiation
Interactions involving this protein in SubtInteract: RapA
Function and regulation of this protein in SubtiPathways:
Phosphorelay
MW, pI 44 kDa, 4.848
Gene length, protein length 1134 bp, 378 aa
Immediate neighbours yjoB, phrA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RapA context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

protein modification, transcription factors and their control, phosphorelay, quorum sensing

This gene is a member of the following regulons

CodY regulon, ComA regulon, Spo0A regulon

The gene

Basic information

  • Locus tag: BSU12430

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: RAP family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
    • modular organization comprising an amino terminal alpha-helical domain connected to a domain formed by six tetratricopeptide (TPR) repeats PubMed
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed by glucose (4.2-fold) (CcpA) PubMed
    • repressed by casamino acids PubMed
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
    • expressed at high cell density (ComA) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed