Difference between revisions of "GdpP"

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m (moved YybT to GdpP: 22211522)
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|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''yybT''
+
|''gdpP''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
+
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yybT ''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:''' ''[[yybS]]-[[yybT]]-[[rplI]]'' (according to [http://dbtbs.hgc.jp/COG/prom/yybST-rplI.html DBTBS])
+
* '''Operon:''' ''[[yybS]]-[[gdpP]]-[[rplI]]'' (according to [http://dbtbs.hgc.jp/COG/prom/yybST-rplI.html DBTBS])
  
 
* '''[[Sigma factor]]:'''  
 
* '''[[Sigma factor]]:'''  
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=Biological materials =
 
=Biological materials =
  
* '''Mutant:''' YA188 ''[[yybT]]::spc'',  available in [[Stülke]] lab
+
* '''Mutant:''' YA188 ''[[gdpP]]::spc'',  available in [[Stülke]] lab
** GP998 (''[[yybT]]''::''spc''), available in [[Stülke]] lab
+
** GP998 (''[[gdpP]]''::''spc''), available in [[Stülke]] lab
  
 
* '''Expression vector:'''
 
* '''Expression vector:'''
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'''Additional publications:''' {{PubMed|22211522}}
 
'''Additional publications:''' {{PubMed|22211522}}
 
<pubmed> 19901023 21257773    21566650</pubmed>
 
<pubmed> 19901023 21257773    21566650</pubmed>
==YybT homologs in other organisms==
+
==GdpP homologs in other organisms==
 
<pubmed> 18502872  </pubmed>
 
<pubmed> 18502872  </pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 17:30, 9 January 2012

  • Description: cyclic di-AMP phosphodiesterase



Gene name gdpP
Synonyms yybT
Essential no
Product c-di-AMP phosphodiesterase
Function control of sporulation initiation, cell wall homeostasis
MW, pI 74 kDa, 4.865
Gene length, protein length 1977 bp, 659 aa
Immediate neighbours rplI, yybS
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YybT context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

metabolism of signalling nucleotides

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU40510

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: cyclic dinucleotide phosphodiesterase, hydrolysis of di-cyclic AMP PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
    • N-terminal domain that shares minimum sequence homology with Per-ARNT-Sim (PAS) domains PubMed
  • Modification:
  • Cofactor(s): b-type heme with 1:1 stoichiometry PubMed
  • Effectors of protein activity:
    • ppGpp inhibits cyclic dinucleotide phosphodiesterase activity PubMed
    • Heme binding suppresses phosphodiesterase activity PubMed
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

GdpP homologs in other organisms