Difference between revisions of "PheS"
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* '''Operon:''' ''[[pheS]]-[[pheT]]'' {{PubMed|2127701}} | * '''Operon:''' ''[[pheS]]-[[pheT]]'' {{PubMed|2127701}} | ||
| − | * '''[ | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pheS_2929438_2930472_-1 pheS] {{PubMed|22383849}} |
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| + | * '''Sigma factor:''' [[SigA]] {{PubMed|2127701}} | ||
* '''Regulation:''' | * '''Regulation:''' | ||
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** [[T-box]]: [[RNA switch]], transcriptional antitermination {{PubMed|19258532}} | ** [[T-box]]: [[RNA switch]], transcriptional antitermination {{PubMed|19258532}} | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 14:49, 16 April 2012
- Description: phenylalanyl-tRNA synthetase (alpha subunit), universally conserved protein
| Gene name | pheS |
| Synonyms | |
| Essential | yes PubMed |
| Product | phenylalanyl-tRNA synthetase (alpha subunit) |
| Function | translation |
| Interactions involving this protein in SubtInteract: PheS | |
| Metabolic function and regulation of this protein in SubtiPathways: tRNA charging | |
| MW, pI | 38 kDa, 5.083 |
| Gene length, protein length | 1032 bp, 344 aa |
| Immediate neighbours | pheT, ysgA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
translation, essential genes, universally conserved proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU28640
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe) (according to Swiss-Prot)
- Protein family: Phe-tRNA synthetase alpha chain type 1 subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- UniProt: P17921
- KEGG entry: [3]
- E.C. number: 6.1.1.20
Additional information
Expression and regulation
- Regulatory mechanism:
- T-box: RNA switch, transcriptional antitermination PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
