Difference between revisions of "LicR"

From SubtiWiki
Jump to: navigation, search
Line 108: Line 108:
 
* '''Operon:''' ''licR'' {{PubMed|8990303}}  
 
* '''Operon:''' ''licR'' {{PubMed|8990303}}  
  
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|8990303}}  
+
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=licR_3962003_3963928_-1 licR] {{PubMed|22383849}}
 +
 
 +
* '''Sigma factor:''' [[SigA]] {{PubMed|8990303}}  
  
 
* '''Regulation:'''
 
* '''Regulation:'''

Revision as of 09:30, 17 April 2012

Gene name licR
Synonyms celR
Essential no
Product transcriptional activator, PRD-type
Function regulation of lichenan utilization
Interactions involving this protein in SubtInteract: LicR
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism
MW, pI 73 kDa, 6.115
Gene length, protein length 1923 bp, 641 aa
Immediate neighbours licB, yxzF
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
LicR context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control, phosphoproteins

This gene is a member of the following regulons

The LicR regulon:

The gene

Basic information

  • Locus tag: BSU38600

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Protein EIIA N(pi)-phospho-L-histidine + protein EIIB = protein EIIA + protein EIIB N(pi)-phospho-L-histidine/cysteine (according to Swiss-Prot)
  • Protein family: transcriptional antiterminator bglG family (according to Swiss-Prot), Attention: this is wrong: LicR is a transcription activator, the similarity to the BglG family is limited to the PTS-regulation domains
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

S Tobisch, J Stülke, M Hecker
Regulation of the lic operon of Bacillus subtilis and characterization of potential phosphorylation sites of the LicR regulator protein by site-directed mutagenesis.
J Bacteriol: 1999, 181(16);4995-5003
[PubMed:10438772] [WorldCat.org] [DOI] (P p)

S Tobisch, P Glaser, S Krüger, M Hecker
Identification and characterization of a new beta-glucoside utilization system in Bacillus subtilis.
J Bacteriol: 1997, 179(2);496-506
[PubMed:8990303] [WorldCat.org] [DOI] (P p)