Difference between revisions of "YonN"

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(Basic information/ Evolution)
(Extended information on the protein)
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* '''[[SubtInteract|Interactions]]:'''
  
* '''Localization:'''
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=== Database entries ===
 
=== Database entries ===

Revision as of 14:29, 30 September 2011

  • Description: similar to HU-related DNA-binding protein

Gene name yonN
Synonyms
Essential no
Product unknown
Function unknown
MW, pI 9 kDa, 10.227
Gene length, protein length 276 bp, 92 aa
Immediate neighbours yonO, yonK
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YonN context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

genetics/ other, SP-beta prophage

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU21050

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • YonN-mediated untwisting of the DNA stimulates Nth endonuclease activity at AP sites PubMed
  • Protein family: glycosyltransferase 1 family (according to Swiss-Prot)
  • Paralogous protein(s): Hbs

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Christopher Collier, Cristina Machón, Geoff S Briggs, Wiep Klaas Smits, Panos Soultanas
Untwisting of the DNA helix stimulates the endonuclease activity of Bacillus subtilis Nth at AP sites.
Nucleic Acids Res: 2012, 40(2);739-50
[PubMed:21954439] [WorldCat.org] [DOI] (I p)