Difference between revisions of "PutR"
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|''putR'' | |''putR'' | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ycgP '' | + | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ycgP, prcR '' |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' transcription activation of the proline utilization operon ''[[putB]]-[[putC]]-[[putP]]'' in the presence of proline {{PubMed|21840319}} | + | * '''Catalyzed reaction/ biological activity:''' transcription activation of the proline utilization operon ''[[putB]]-[[putC]]-[[putP]]'' in the presence of proline {{PubMed|21840319,21964733}} |
* '''Protein family:''' cdaR family (according to Swiss-Prot) | * '''Protein family:''' cdaR family (according to Swiss-Prot) | ||
| Line 101: | Line 101: | ||
* '''Operon:''' ''[[putR]]'' {{PubMed|21840319}} | * '''Operon:''' ''[[putR]]'' {{PubMed|21840319}} | ||
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|21964733}} |
| − | * '''Regulation:''' constitutively expressed {{PubMed|21840319}} | + | * '''Regulation:''' constitutively expressed {{PubMed|21840319,21964733}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| Line 128: | Line 128: | ||
=References= | =References= | ||
| − | <pubmed> 21840319 </pubmed> | + | <pubmed> 21840319 21964733</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 09:25, 6 October 2011
| Gene name | putR |
| Synonyms | ycgP, prcR |
| Essential | no |
| Product | transcriptional activator |
| Function | regulation of proline utilization |
| MW, pI | 47 kDa, 5.37 |
| Gene length, protein length | 1233 bp, 411 aa |
| Immediate neighbours | putP, ycgQ |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
transcription factors and their control, utilization of amino acids
This gene is a member of the following regulons
The PutR regulon:
The gene
Basic information
- Locus tag: BSU03230
Phenotypes of a mutant
- no growth with proline as single source of carbon or nitrogen PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transcription activation of the proline utilization operon putB-putC-putP in the presence of proline PubMed
- Protein family: cdaR family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s): proline acts as co-activator PubMed
- Effectors of protein activity: proline activates PutR PubMed
- Interactions:
Database entries
- Structure:
- UniProt: P94393
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation: constitutively expressed PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Shih-Chien Huang, Ta-Hui Lin, Gwo-Chyuan Shaw
PrcR, a PucR-type transcriptional activator, is essential for proline utilization and mediates proline-responsive expression of the proline utilization operon putBCP in Bacillus subtilis.
Microbiology (Reading): 2011, 157(Pt 12);3370-3377
[PubMed:21964733]
[WorldCat.org]
[DOI]
(I p)
Boris R Belitsky
Indirect repression by Bacillus subtilis CodY via displacement of the activator of the proline utilization operon.
J Mol Biol: 2011, 413(2);321-36
[PubMed:21840319]
[WorldCat.org]
[DOI]
(I p)
