Difference between revisions of "FlhF"
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| − | * '''Description:''' | + | * '''Description:''' signal recognition particle-like GTPase, placement and assembly of flagella <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || signal recognition particle-GTPase | + | |style="background:#ABCDEF;" align="center"| '''Product''' || signal recognition particle-like GTPase |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || placement and assembly of polar flagella | |style="background:#ABCDEF;" align="center"|'''Function''' || placement and assembly of polar flagella | ||
| + | |- | ||
| + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/FlhF FlhF] | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 40 kDa, 8.719 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 40 kDa, 8.719 | ||
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=== Additional information=== | === Additional information=== | ||
| − | |||
| − | |||
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* '''Catalyzed reaction/ biological activity:''' | * '''Catalyzed reaction/ biological activity:''' | ||
| + | ** GTPase activity {{PubMed|22056770}} | ||
| + | ** placement of the first flagellar protein, [[FliF]] {{PubMed|22056770}} | ||
| + | |||
* '''Protein family:''' GTP-binding SRP family (according to Swiss-Prot) | * '''Protein family:''' GTP-binding SRP family (according to Swiss-Prot) | ||
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| + | ** interaction with [[YlxH]] activates the GTPase activity of [[FlhF]] {{PubMed|22056770}} | ||
* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
| + | ** [[YlxH]]-[[FlhF]] ([[YlxH]] binds the GTP-bound homodimer of [[FlhF]]) {{PubMed|22056770}} | ||
* '''[[Localization]]:''' cell membrane (according to Swiss-Prot) | * '''[[Localization]]:''' cell membrane (according to Swiss-Prot) | ||
| Line 87: | Line 92: | ||
=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2PX3 2PX3] (complexed with GTP-Mg2+) | + | * '''Structure:''' |
| + | ** [http://www.rcsb.org/pdb/explore.do?structureId=2PX3 2PX3] (complexed with GTP-Mg2+) {{PubMed|17699634}} | ||
| + | ** [http://www.rcsb.org/pdb/explore.do?structureId=3SYN 3SYN] (complex with its activator [[YlxH]]) {{PubMed|22056770}} | ||
* '''UniProt:''' [http://www.uniprot.org/uniprot/Q01960 Q01960] | * '''UniProt:''' [http://www.uniprot.org/uniprot/Q01960 Q01960] | ||
| Line 136: | Line 143: | ||
=References= | =References= | ||
| − | <pubmed>1447978,17699634,17850253,15317803,14651647, 9657996,8157612,15175317</pubmed> | + | <pubmed>1447978,17699634,17850253,15317803,14651647, 9657996,8157612,15175317 22056770 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 09:56, 8 November 2011
- Description: signal recognition particle-like GTPase, placement and assembly of flagella
| Gene name | flhF |
| Synonyms | |
| Essential | no |
| Product | signal recognition particle-like GTPase |
| Function | placement and assembly of polar flagella |
| Interactions involving this protein in SubtInteract: FlhF | |
| MW, pI | 40 kDa, 8.719 |
| Gene length, protein length | 1098 bp, 366 aa |
| Immediate neighbours | flhA, ylxH |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
motility and chemotaxis, membrane proteins
This gene is a member of the following regulons
CodY regulon, SigD regulon, Spo0A regulon
The gene
Basic information
- Locus tag: BSU16400
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: GTP-binding SRP family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- UniProt: Q01960
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
