Difference between revisions of "TuaD"

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(Extended information on the protein)
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* '''Operon:''' ''[[tuaA]]-[[tuaB]]-[[tuaC]]-[[tuaD]]-[[tuaE]]-[[tuaF]]-[[tuaG]]-[[tuaH]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/10048024 PubMed]
 
* '''Operon:''' ''[[tuaA]]-[[tuaB]]-[[tuaC]]-[[tuaD]]-[[tuaE]]-[[tuaF]]-[[tuaG]]-[[tuaH]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/10048024 PubMed]
  
* '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/10048024 PubMed]
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=tuaD_3654139_3655524_-1 tuaD] {{PubMed|22383849}}
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* '''Sigma factor:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/10048024 PubMed]
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  

Revision as of 07:41, 17 April 2012

  • Description: UDP glucose 6-dehydrogenase

Gene name tuaD
Synonyms yvhD
Essential no
Product UDP glucose 6-dehydrogenase
Function biosynthesis of teichuronic acid
Interactions involving this protein in SubtInteract: TuaD
MW, pI 49 kDa, 6.107
Gene length, protein length 1383 bp, 461 aa
Immediate neighbours tuaE, tuaC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
TuaD context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components

This gene is a member of the following regulons

PhoP regulon

The gene

Basic information

  • Locus tag: BSU35580

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: UDP-glucose + 2 NAD+ + H2O = UDP-glucuronate + 2 NADH (according to Swiss-Prot)
  • Protein family: UDP-glucose/GDP-mannose dehydrogenase family (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Cofactor(s):
  • Effectors of protein activity: PtkA-dependent phosphorylation stimulates TuaD activity PubMed

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • expressed under conditions of phosphate limitation (PhoP) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References