Dps

• Description: iron storage protein, general stress protein, resistance against ethanol stress and survival at low temperatures
  
  

Gene name	dps
Synonyms	ytkB
Essential	no
Product	mini-ferritin
Function	iron storage
MW, pI	16 kDa, 4.444
Gene length, protein length	435 bp, 145 aa
Immediate neighbours	ytkC, ytkA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

acquisition of iron, iron metabolism, general stress proteins (controlled by SigB)

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

• Locus tag: BSU30650

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: dps family (according to Swiss-Prot)

• Paralogous protein(s): MrgA

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P80879

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: dps PubMed

• Expression browser: dps PubMed

• Sigma factor: SigB PubMed

• Regulation:
  • induced by stress (SigB) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Emilia Chiancone, Pierpaolo Ceci, Andrea Ilari, Frederica Ribacchi, Simonetta Stefanini
Iron and proteins for iron storage and detoxification.
Biometals: 2004, 17(3);197-202
[PubMed:15222465] [WorldCat.org] [DOI] (P p)

Original publications

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)

H Antelmann, S Engelmann, R Schmid, A Sorokin, A Lapidus, M Hecker
Expression of a stress- and starvation-induced dps/pexB-homologous gene is controlled by the alternative sigma factor sigmaB in Bacillus subtilis.
J Bacteriol: 1997, 179(23);7251-6
[PubMed:9393687] [WorldCat.org] [DOI] (P p)

M Bozzi, G Mignogna, S Stefanini, D Barra, C Longhi, P Valenti, E Chiancone
A novel non-heme iron-binding ferritin related to the DNA-binding proteins of the Dps family in Listeria innocua.
J Biol Chem: 1997, 272(6);3259-65
[PubMed:9013563] [WorldCat.org] [DOI] (P p)