Difference between revisions of "SasA"
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* '''Operon:''' ''ywaC'' {{PubMed|11866510}} | * '''Operon:''' ''ywaC'' {{PubMed|11866510}} | ||
| − | * '''[[Sigma factor]]:''' [[SigW]] {{PubMed|11866510}} | + | * '''[[Sigma factor]]:''' [[SigM]] {{PubMed|18179421}} [[SigW]] {{PubMed|11866510}} |
* '''Regulation:''' Transcription is highly upregulated in response to lesions in late-acting teichoic acid synthesis genes ''[[tagB]]'', ''[[tagD]]'' and ''[[tagF]]'', and also in response to cell-wall-active compounds like bacitracin or vancomycin {{PubMed|19477419}} | * '''Regulation:''' Transcription is highly upregulated in response to lesions in late-acting teichoic acid synthesis genes ''[[tagB]]'', ''[[tagD]]'' and ''[[tagF]]'', and also in response to cell-wall-active compounds like bacitracin or vancomycin {{PubMed|19477419}} | ||
Revision as of 15:01, 18 May 2011
- Description: (p)ppGpp synthetase, small alarmone synthetase
| Gene name | ywaC |
| Synonyms | ipa-7d |
| Essential | no |
| Product | (p)ppGpp synthetase |
| Function | ppGpp synthesis independent from stringent response |
| MW, pI | 24 kDa, 6.217 |
| Gene length, protein length | 630 bp, 210 aa |
| Immediate neighbours | ywaD, menA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
metabolism of signalling nucleotides, cell envelope stress proteins (controlled by SigM, W, X, Y)
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU38480
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): YjbM
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P39583
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: ywaC PubMed
- Regulation: Transcription is highly upregulated in response to lesions in late-acting teichoic acid synthesis genes tagB, tagD and tagF, and also in response to cell-wall-active compounds like bacitracin or vancomycin PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
