Difference between revisions of "MutS"

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* '''Description:''' DNA mismatch repair (recognition) <br/><br/>
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* '''Description:''' DNA mismatch repair (mismatch recognition protein) <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || DNA mismatch repair (recognition)
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|style="background:#ABCDEF;" align="center"| '''Product''' || mismatch recognition protein
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || DNA repair
 
|style="background:#ABCDEF;" align="center"|'''Function''' || DNA repair
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:'''
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* '''[[SubtInteract|Interactions]]:'''
 +
** [[MutS]]-[[DnaN]] {{PubMed|20453097}}
 +
** [[DnaE]]-[[MutS]]  {{PubMed|21958350}}
  
* '''Localization:''' Nucleoid (Mid-cell) [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed]
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* '''[[Localization]]:'''
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** forms foci at midcell position, the frequency of foci increases upon mismatch formation {{PubMed|21958350}}
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** Nucleoid (Mid-cell) [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed]
  
 
=== Database entries ===
 
=== Database entries ===
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=References=
 
=References=
 
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'''Additional publications:''' {{PubMed|21958350}}
<pubmed>8760914, 15375129,16479537 20525796</pubmed>
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<pubmed>8760914, 15375129,16479537 20525796 20453097 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 12:07, 24 October 2011

  • Description: DNA mismatch repair (mismatch recognition protein)

Gene name mutS
Synonyms
Essential no
Product mismatch recognition protein
Function DNA repair
MW, pI 97 kDa, 5.189
Gene length, protein length 2574 bp, 858 aa
Immediate neighbours cotE, mutL
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
MutS context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

DNA repair/ recombination

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU17040

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: DNA mismatch repair mutS family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:
    • forms foci at midcell position, the frequency of foci increases upon mismatch formation PubMed
    • Nucleoid (Mid-cell) PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:

Biological materials

  • Mutant: GP1190 (del mutSL::aphA3) available in the Stülke lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed