Difference between revisions of "YjbH"
| Line 52: | Line 52: | ||
=== Additional information=== | === Additional information=== | ||
| − | |||
| − | |||
| − | |||
=The protein= | =The protein= | ||
| Line 109: | Line 106: | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| + | ** A [[ncRNA]] is predicted between ''[[yizD]]'' and ''[[yjbH]]'' {{PubMed|20525796}} | ||
=Biological materials = | =Biological materials = | ||
| Line 139: | Line 137: | ||
==Original Publications== | ==Original Publications== | ||
'''Additional publications:''' {{PubMed|21378193}} | '''Additional publications:''' {{PubMed|21378193}} | ||
| − | <pubmed>17293416, 19074380 17908206, </pubmed> | + | <pubmed>17293416, 19074380 17908206, 20525796</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 18:53, 4 May 2011
- Description: adaptor protein for ClpX-ClpP-catalyzed Spx degradation, confers resistance against nitrosylating agents
| Gene name | yjbH |
| Synonyms | |
| Essential | no |
| Product | adaptor protein |
| Function | stimulation of Spx degradation |
| MW, pI | 31 kDa, 5.206 |
| Gene length, protein length | 825 bp, 275 aa |
| Immediate neighbours | pepF, yjbI |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU11550
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: adaptor protein for ClpX-ClpP-catalyzed Spx degradation PubMed
- Protein family: UPF0413 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):contains Zn atoms (coordinated by the N-terminal His-rich region) PubMed
- Effectors of protein activity:
- Localization: cytosolic protein
Database entries
- Structure:
- UniProt: O31606
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Peter Zuber, Oregon Health and Science University, USA Homepage
Claes von Wachenfeldt, Lund University, Sweden Homepage
Your additional remarks
References
Reviews: PubMed
Original Publications
Additional publications: PubMed
Irnov Irnov, Cynthia M Sharma, Jörg Vogel, Wade C Winkler
Identification of regulatory RNAs in Bacillus subtilis.
Nucleic Acids Res: 2010, 38(19);6637-51
[PubMed:20525796]
[WorldCat.org]
[DOI]
(I p)
Saurabh K Garg, Sushma Kommineni, Luke Henslee, Ying Zhang, Peter Zuber
The YjbH protein of Bacillus subtilis enhances ClpXP-catalyzed proteolysis of Spx.
J Bacteriol: 2009, 191(4);1268-77
[PubMed:19074380]
[WorldCat.org]
[DOI]
(I p)
Jonas T Larsson, Annika Rogstam, Claes von Wachenfeldt
YjbH is a novel negative effector of the disulphide stress regulator, Spx, in Bacillus subtilis.
Mol Microbiol: 2007, 66(3);669-84
[PubMed:17908206]
[WorldCat.org]
[DOI]
(P p)
Annika Rogstam, Jonas T Larsson, Peter Kjelgaard, Claes von Wachenfeldt
Mechanisms of adaptation to nitrosative stress in Bacillus subtilis.
J Bacteriol: 2007, 189(8);3063-71
[PubMed:17293416]
[WorldCat.org]
[DOI]
(P p)
