Difference between revisions of "GreA"
(→Original Publications) |
|||
| Line 1: | Line 1: | ||
| − | * '''Description:''' transcription elongation factor <br/><br/> | + | * '''Description:''' transcription elongation factor, resolves stalled [[RNA polymerase]] at promoter or promoter-proximal regions, <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 32: | Line 32: | ||
= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
| − | {{SubtiWiki category|[[transcription | + | {{SubtiWiki category|[[transcription]]}} |
| − | |||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| Line 53: | Line 52: | ||
=== Additional information=== | === Additional information=== | ||
| − | |||
| − | |||
| Line 81: | Line 78: | ||
* '''Interactions:''' | * '''Interactions:''' | ||
| − | * '''Localization:''' | + | * '''Localization:''' uniformly distributed throughout the nucleoid {{PubMed|16707701}} |
=== Database entries === | === Database entries === | ||
Revision as of 09:01, 26 April 2011
- Description: transcription elongation factor, resolves stalled RNA polymerase at promoter or promoter-proximal regions,
| Gene name | greA |
| Synonyms | |
| Essential | no |
| Product | transcription elongation factor |
| Function | transcription elongation |
| MW, pI | 17 kDa, 4.475 |
| Gene length, protein length | 471 bp, 157 aa |
| Immediate neighbours | pbpI, udk |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU27320
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: greA/greB family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: uniformly distributed throughout the nucleoid PubMed
Database entries
- Structure:
- UniProt: P80240
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Padraig Deighan, Ann Hochschild
Conformational toggle triggers a modulator of RNA polymerase activity.
Trends Biochem Sci: 2006, 31(8);424-6
[PubMed:16815708]
[WorldCat.org]
[DOI]
(P p)
Sergei Borukhov, Jookyung Lee, Oleg Laptenko
Bacterial transcription elongation factors: new insights into molecular mechanism of action.
Mol Microbiol: 2005, 55(5);1315-24
[PubMed:15720542]
[WorldCat.org]
[DOI]
(P p)
Bryce E Nickels, Ann Hochschild
Regulation of RNA polymerase through the secondary channel.
Cell: 2004, 118(3);281-4
[PubMed:15294154]
[WorldCat.org]
[DOI]
(P p)
Original Publications
Mohammad Roghanian, Yulia Yuzenkova, Nikolay Zenkin
Controlled interplay between trigger loop and Gre factor in the RNA polymerase active centre.
Nucleic Acids Res: 2011, 39(10);4352-9
[PubMed:21266474]
[WorldCat.org]
[DOI]
(I p)
Geoff P Doherty, Donna H Meredith, Peter J Lewis
Subcellular partitioning of transcription factors in Bacillus subtilis.
J Bacteriol: 2006, 188(11);4101-10
[PubMed:16707701]
[WorldCat.org]
[DOI]
(P p)
