Difference between revisions of "FabL"

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(Database entries)
(Original Publications)
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<pubmed> 15952903 17919287</pubmed>
 
<pubmed> 15952903 17919287</pubmed>
 
==Original Publications==
 
==Original Publications==
<pubmed>17114254, 10463184 15699190 8755877 11007778 21185310 </pubmed>
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<pubmed>17114254, 10463184 15699190 8755877 11007778 </pubmed>
 
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'''Additional publications:''' {{PubMed|21185310}}
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 17:42, 10 January 2011

  • Description: enoyl-acyl carrier protein reductase

Gene name fabL
Synonyms yfhR, ygaA
Essential no
Product enoyl-acyl carrier protein reductase
Function fatty acid biosynthesis
Metabolic function and regulation of this protein in SubtiPathways:
Lipid synthesis
MW, pI 27 kDa, 5.967
Gene length, protein length 750 bp, 250 aa
Immediate neighbours yfhS, sspE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
FabL context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

biosynthesis of lipids, sporulation proteins

This gene is a member of the following regulons

SigG regulon, YfhP regulon

The gene

Basic information

  • Locus tag: BSU08650

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): FabI, one of the two proteins has to be present for viability PubMed

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original Publications

Helena B Thomaides, Ella J Davison, Lisa Burston, Hazel Johnson, David R Brown, Alison C Hunt, Jeffery Errington, Lloyd Czaplewski
Essential bacterial functions encoded by gene pairs.
J Bacteriol: 2007, 189(2);591-602
[PubMed:17114254] [WorldCat.org] [DOI] (P p)

Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190] [WorldCat.org] [DOI] (P p)

R J Heath, N Su, C K Murphy, C O Rock
The enoyl-[acyl-carrier-protein] reductases FabI and FabL from Bacillus subtilis.
J Biol Chem: 2000, 275(51);40128-33
[PubMed:11007778] [WorldCat.org] [DOI] (P p)

Hiroki Yamamoto, Masao Mori, Junichi Sekiguchi
Transcription of genes near the sspE locus of the Bacillus subtilis genome.
Microbiology (Reading): 1999, 145 ( Pt 8);2171-2180
[PubMed:10463184] [WorldCat.org] [DOI] (P p)

I Bagyan, J Hobot, S Cutting
A compartmentalized regulator of developmental gene expression in Bacillus subtilis.
J Bacteriol: 1996, 178(15);4500-7
[PubMed:8755877] [WorldCat.org] [DOI] (P p)

Additional publications: PubMed