Difference between revisions of "DynA"
| Line 1: | Line 1: | ||
| − | * '''Description:''' | + | * '''Description:''' dynamin-like protein, mediates membrane fusion<br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || dynamin-like protein |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || fusion of membranes |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 137 kDa, 5.724 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 137 kDa, 5.724 | ||
| Line 62: | Line 62: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' mediates nucleotide independent membrane fusion ''in vitro'' {{PubMed|21205012}} |
| + | |||
* '''Protein family:''' gerABKA family (according to Swiss-Prot) | * '''Protein family:''' gerABKA family (according to Swiss-Prot) | ||
| Line 72: | Line 73: | ||
* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' | + | * '''Domains:''' two separate dynamin-like subunits and GTPase domains {{PubMed|21205012}} |
* '''Modification:''' | * '''Modification:''' | ||
| − | * '''Cofactor(s):''' | + | * '''Cofactor(s):''' Mg(2+) {{PubMed|21205012}} |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| Line 129: | Line 130: | ||
=References= | =References= | ||
| − | <pubmed> 8396117</pubmed> | + | <pubmed> 8396117 21205012 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 13:27, 6 January 2011
- Description: dynamin-like protein, mediates membrane fusion
| Gene name | dynA |
| Synonyms | ypbR |
| Essential | no |
| Product | dynamin-like protein |
| Function | fusion of membranes |
| MW, pI | 137 kDa, 5.724 |
| Gene length, protein length | 3579 bp, 1193 aa |
| Immediate neighbours | ypbS, fbpC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU22030
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: mediates nucleotide independent membrane fusion in vitro PubMed
- Protein family: gerABKA family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains: two separate dynamin-like subunits and GTPase domains PubMed
- Modification:
- Cofactor(s): Mg(2+) PubMed
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P54159
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: ypbR PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Frank Bürmann, Nina Ebert, Suey van Baarle, Marc Bramkamp
A bacterial dynamin-like protein mediating nucleotide-independent membrane fusion.
Mol Microbiol: 2011, 79(5);1294-304
[PubMed:21205012]
[WorldCat.org]
[DOI]
(I p)
L Chen, L P James, J D Helmann
Metalloregulation in Bacillus subtilis: isolation and characterization of two genes differentially repressed by metal ions.
J Bacteriol: 1993, 175(17);5428-37
[PubMed:8396117]
[WorldCat.org]
[DOI]
(P p)
