Difference between revisions of "QdoI"

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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1011 bp, 337 aa  
 
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1011 bp, 337 aa  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yxaH]]'', ''[[yxaF]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yxaH]]'', ''[[qdoR]]''
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB16035&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
 
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB16035&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
 
{{SubtiWiki regulon|[[LmrA regulon]]}},
 
{{SubtiWiki regulon|[[LmrA regulon]]}},
{{SubtiWiki regulon|[[YxaF regulon]]}}
+
{{SubtiWiki regulon|[[QdoR regulon]]}}
  
 
=The gene=
 
=The gene=
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=== Additional information===
 
=== Additional information===
 
 
  
  
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* '''Regulation:'''  
 
* '''Regulation:'''  
** induced by flavonoids such as quercetin ([[YxaF]], [[LmrA]]) {{PubMed|17483215}}
+
** induced by flavonoids such as quercetin ([[QdoR]], [[LmrA]]) {{PubMed|17483215}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 
** [[LmrA]]: transcription repression {{PubMed|15317768}}
 
** [[LmrA]]: transcription repression {{PubMed|15317768}}
** [[YxaF]]: transcription repression {{PubMed|17483215}}
+
** [[QdoR]]: transcription repression {{PubMed|17483215}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''

Revision as of 17:20, 10 July 2011

  • Description: Fe-containing quercetin 2,3-dioxygenase

Gene name qdoI
Synonyms yxaG
Essential no
Product Fe-containing quercetin 2,3-dioxygenase
Function resistance to plant product quercetin
MW, pI 37,4 kDa, 5.562
Gene length, protein length 1011 bp, 337 aa
Immediate neighbours yxaH, qdoR
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YxaG context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)

This gene is a member of the following regulons

LmrA regulon, QdoR regulon

The gene

Basic information

  • Locus tag: BSU39980

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Quercetin + O2 = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO + H+ (according to Swiss-Prot)
  • Protein family:bicupin family
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s): Fe(2+)
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References