FliS

• Description: chaperone for the export of flagellin
  
  

Gene name	fliS
Synonyms
Essential	no
Product	chaperone for flagellin export
Function	motility and chemotaxis
Interactions involving this protein in SubtInteract: FliS
MW, pI	14 kDa, 5.229
Gene length, protein length	399 bp, 133 aa
Immediate neighbours	fliT, fliD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

motility and chemotaxis

This gene is a member of the following regulons

SigD regulon

The gene

Basic information

• Locus tag: BSU35330

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: fliS family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: FliS-Hag PubMed, FlhA-(FliS-Hag) PubMed

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure: 1VH6

• UniProt: P39739

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yvyC-fliD-fliS-fliT PubMed

• Sigma factor: SigD PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Gert Bange, Nico Kümmerer, Christoph Engel, Gunes Bozkurt, Klemens Wild, Irmgard Sinning
FlhA provides the adaptor for coordinated delivery of late flagella building blocks to the type III secretion system.
Proc Natl Acad Sci U S A: 2010, 107(25);11295-300
[PubMed:20534509] [WorldCat.org] [DOI] (I p)

L Chen, J D Helmann
The Bacillus subtilis sigma D-dependent operon encoding the flagellar proteins FliD, FliS, and FliT.
J Bacteriol: 1994, 176(11);3093-101
[PubMed:8195064] [WorldCat.org] [DOI] (P p)