YszB

• Description: chorismate mutase
  
  

Gene name	pheB
Synonyms
Essential	no
Product	chorismate mutase
Function	biosynthesis of phenylalanine
Metabolic function and regulation of this protein in SubtiPathways: Phe, Tyr, Trp
MW, pI	16 kDa, 6.36
Gene length, protein length	441 bp, 147 aa
Immediate neighbours	pheA, obg
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

biosynthesis/ acquisition of amino acids

The gene

Basic information

• Locus tag: BSU27910

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: UPF0735 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P21204

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: pheB-pheA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Frederik Claeyssens, Kara E Ranaghan, Narin Lawan, Stephen J Macrae, Frederick R Manby, Jeremy N Harvey, Adrian J Mulholland
Analysis of chorismate mutase catalysis by QM/MM modelling of enzyme-catalysed and uncatalysed reactions.
Org Biomol Chem: 2011, 9(5);1578-90
[PubMed:21243152] [WorldCat.org] [DOI] (I p)

K Trach, J A Hoch
The Bacillus subtilis spo0B stage 0 sporulation operon encodes an essential GTP-binding protein.
J Bacteriol: 1989, 171(3);1362-71
[PubMed:2537815] [WorldCat.org] [DOI] (P p)