YncD

• Description: alanine racemase
  
  

Gene name	yncD
Synonyms	alrB
Essential	no
Product	alanine racemase
Function	unknown
Metabolic function and regulation of this protein in SubtiPathways: Alternative nitrogen sources
MW, pI	43 kDa, 9.593
Gene length, protein length	1182 bp, 394 aa
Immediate neighbours	yncC, yncE
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

sporulation proteins, poorly characterized/ putative enzymes

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

• Locus tag: BSU17640

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: L-alanine = D-alanine (according to Swiss-Prot)

• Protein family: alanine racemase family (according to Swiss-Prot)

• Paralogous protein(s): Alr

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P94494

• KEGG entry: [3]

• E.C. number: 5.1.1.1

Expression and regulation

• Operon: yncD (according to DBTBS)

• Sigma factor: SigE PubMed

• Regulation:
  • expressed during sporulation in the mother cell (SigE) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Kara J Pierce, Samson P Salifu, Martin Tangney
Gene cloning and characterization of a second alanine racemase from Bacillus subtilis encoded by yncD.
FEMS Microbiol Lett: 2008, 283(1);69-74
[PubMed:18399999] [WorldCat.org] [DOI] (P p)

Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190] [WorldCat.org] [DOI] (P p)

Andrea Feucht, Louise Evans, Jeff Errington
Identification of sporulation genes by genome-wide analysis of the sigmaE regulon of Bacillus subtilis.
Microbiology (Reading): 2003, 149(Pt 10);3023-3034
[PubMed:14523133] [WorldCat.org] [DOI] (P p)